UCPH, Denmark – PhD Scholarship in Nutritional Immunology – Oct 2021

University of Copenhagen (UCPH)

Denmark

The Nutritional Immunology Lab at Department of Biomedical Sciences, UCPH, invites applications for Fully funded PhD Scholarship led by Assist. Professor Benjamin A. H. Jensen, Denmark

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General Info

Position: PhD Scholarship
No. of Positions: 1
Research Field: , ,
Deadline to Apply: Expired
Joining Date: Jan 01, 2022
Contract Period: 3 Years
Salary: According to Standard Norms

Workplace:
Faculty of Health and Medical Sciences
Department of Biomedical Sciences
University of Copenhagen (UCPH)
Copenhagen,

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Qualification Details

You are 1) Curious, talented and highly motivated with an MSc in Molecular Biomedicine, Biochemistry, Immunology or equivalent; 2) Interested in fundamental scientific discoveries and their translational potential; 3) FELASA accredited. Additionally, you preferably has the follwoing: A) Proven track record in scientific and experimental independence, career stage considered; B) Experience with germ free mice and experimental competences within ex vivo and in vitro cell signalling assays as well as cell migration assays; C) Knowledge about the gut microbiota, as well as innate and adaptive immunity; and lastly D) Strong statistical knowledge including programming skills (statistical and graphical) in R and/or Python.

Responsibilities/Job Description

We design and executive experiments that lead to the discovery of promiscuous microbes that under certain physiological conditions turn from former friends into disease promoting foes in diet-induced obesity. We further explore how to utilize the armoury of host immunity to tweak the behaviour of hostile microbes towards an immune resolving path, hence allowing for a peaceful co-existence between commensal  bacteria and intestinal immune cells in both lean and obese mice. Lastly, we develop a customized experimental diet tailored to target murine liver pathologies resembling clinical manifestations of non-alcoholic steatohepatitis (NASH) and preferably hepatic fibrosis and end stage liver disease. This diet is expected to broaden the research field in preclinical NASH, and thus adding significant value to the molecular understanding of disease progression and hopefully contribute to the development of novel treatment regimens against this devastating disease, with a currently unmet medical need.

How to Apply?

Online Application through "Apply Now" Button from this page or from advertisement webpage (URL below)

Reference Number: -
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Documents Required

The application must include the following documents in PDF format:

1. Motivated letter of application (max. one page)

2. CV incl. education, experience, language skills and other skills relevant for the position

3. Master of Science diploma and transcript of records. If not completed, a certified/signed copy of a recent transcript of records or a written statement from the institution or supervisor will do

4. Publication list (if possible)

About the Project

We dissect how diet components, gut microbial community structures and compartmentalized immunology synergizes to orchestrate host immunometabolism at both gastrointestinal and extra-intestinal origin. We develop and use experimental systems tailored to model human disease with unmet medical needs; first and foremost to improve our molecular understanding of disease progression, and secondly to identify biological factors of therapeutic relevance. Our research spans from diet-induced liver complications over gastrointestinal dysfunction (including IBD, HDP secretion/function, and bacterial translocation), to respiratory complications such as asthma, pulmonary infections, lung immune function and COPD. We are characterized by an innovative mindset and thus – when relevant – strive to identify key (inter)national industry partners to co-develop early discoveries/molecular drug targets to curb human diseases.

About the Department

The Department of Biomedical Sciences is an interdisciplinary and ambitious department covering both fundamental and applied biomedical research. The department has a key focus on translatability, innovation, commercialization and teaching. You will become part of a young, ambitious  and dynamic team that is part of an international and highly collaborative research environment. We encourage innovation and teamwork in part by organizing seminars, journal clubs, and social events. Lastly, we strive to develop every member of the team, enabling him/her to unleash his/her full potential; professionally as well as personally.

About the Employer: University of Copenhagen (UCPH)

Note or Other details

It is conditioned upon the applicant’s success­ful enrolment as a PhD student at the Graduate School at the Faculty of Health and Medical Sciences, University of Copenhagen. This requires submission and acceptance of an application for the specific project formulated by the applicant before the end of 2021, i.e. prior to employment.

The PhD study must be completed in accordance with The Ministerial Order on the PhD programme (2013) and the Faculty’s rules on achieving the degree. Salary, pension and terms of employment are in accordance with the agree­ment between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State.

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Contact details

For specific information about the PhD fellowship, please contact group leader, Benjamin A. H. Jensen; Benjamin.jensen@sund.ku.dk.

General information about PhD study at the Faculty of Health and Medical Sciences is available at the Graduate School’s website: https://healthsciences.ku.dk/phd/guidelines/

Advertisement Details: Fully funded PhD Scholarship in Nutritional Immunology at Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen

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