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Several PhD positions in the field of antiviral drug discovery using Single-Molecule Biophysics -VU Amsterdam, Netherlands, 2022

The Netherlands

The Dulin lab has to offer several fully funded PhD positions (4 years) to start as soon as possible in the field of biophysics to investigate new antiviral drugs targeting RNA viruses, such as coronavirus, enterovirus, flavivirus at Physics of Living System Section of the Physics Department at VU Amsterdam, Netherlands, 2022

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General Info

Position: PhD position
No. of Positions: Several
Research Field: , , , ,
Deadline to Apply: Expired
Joining Date: ASAP
Contract Period: 4 Years
Salary: 2.443 to 3,122 Euro/Month

Faculty of Science

Vrije Universiteit Amsterdam (VU), the Netherlands


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Qualification Details

  • outstanding experimentalists with experience in biophysics, enzymology, biochemistry, physics and molecular biology. Candidates must have a MSc. degree. Experience in optics, computer programming (LabVIEW, Python, Matlab, C++, etc.) and enzymology will be strongly appreciated. If not familiar with programing, the candidates will have to learn Python to process their data.
  • a creative, hard-working and independent individuals with a strong work ethic and a passion to cross research fields. A strong ability to work in team is essential.

They will successfully develop and combine different expertises in physics, biology and software programming to establish new single molecule assays and investigate how novel antivirals drugs interfere with RNA virus genome synthesis. Proficiency in English (both speaking and writing) is required.

Responsibilities/Job Description

The successful candidates will investigate the RNA synthesis machineries of these viruses using state-of-the-art single molecule techniques. Within the lab, the successful candidates will design, perform experiments, and develop new computational analysis tools to analyze their data.

How to Apply?

Application Method: Online Application
Ref. No.: -

Application Procedure

Please apply before 1-7-2022 via the application button and upload your cover letter (one page maximum), a curriculum vitae, a transcript of grades from master and bachelor, a publication list (if relevant) and the contact details of 2-3 references. All the documents must be written in English. The selected applicants are expected to start as soon as possible. The positions will remain open until filled.

About the Department/Section/Group

The Faculty of Science inspires researchers and students to find sustainable solutions for complex societal issues. From forest fires to big data, from obesity to medicines and from molecules to the moon: our teaching and research programmes cover the full spectrum of the natural sciences. We share knowledge and experience with leading research institutes and industries, both here in the Netherlands and abroad.

The Dulin lab has recently relocated its activity at VU Amsterdam from FAU Erlangen-Nuremberg in Germany (https://daviddulinlab.com/). The VU Amsterdam is one of the best universities in the Netherlands, and a leading environment in biophysics, located in the vibrant and international city of Amsterdam. Our team is an inclusive and diverse environment, welcoming excellent students from all backgrounds. We are embedded within the Physics of Living System Section of the Physics Department of VU, together with several other biophysicists, forming a vibrant environment in physics of life, specifically in single molecule biophysics. The Dulin lab has a strong expertise in investigating RNA virus genome synthesis  machinery using single molecule biophysics techniques, with several breakthrough studies on SARS-CoV-2 genome replication and antiviral drugs evaluation (Bera et al., Cell Reports 2021; Seifert et al., eLife 2021). The successful candidates will join an enthusiastic and international team of biophysicists and biochemists ready to tackle highly challenging problems related to antiviral drug discoveries. They will have access to a large variety of cutting-edge assays in single molecule force and fluorescence spectroscopy techniques (e.g. magnetic and optical tweezers, TIRF…), and a molecular biology facility to perform their research. They will also benefit from the support of an experienced staff in molecular biology, biochemistry and data analysis. They will have the opportunity to learn from the best scientists in the field, publish in high-impact journals and present their work at international conferences.

About the Employer:

Note or Other details

A challenging position in a socially involved organization. The salary will be in accordance with university regulations for academic personnel and amounts €2.443 (PhD) per month during the first year and increases to €3,122 (PhD) per month during the fourth year, based on a full-time employment. The job profile: is based on the university job ranking system and is vacant for at least 1 FTE.

The appointment will initially be for 1 year. After a satisfactory evaluation of the initial appointment, the contract will be extended (with three years) for a total duration of 4 years.

Additionally, Vrije Universiteit Amsterdam offers excellent fringe benefits and various schemes and regulations to promote a good work/life balance, such as:

  • a maximum of 41 days of annual leave based on full-time employment
  • 8% holiday allowance and 8.3% end-of-year bonus
  • solid pension scheme (ABP)
  • contribution to commuting expenses
  • optional model for designing a personalized benefits package

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Contact details

Name: Dr. David Dulin
Position: Assistant Professor
E-mail: [email protected]

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