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SDU, Postdoc Job – Life Science, Study Mechanisms of Adipocyte Lineage Determination – Denmark 2022

Denmark, University of Southern Denmark (SDU)

The Mandrup group at the Functional Genomics and Metabolism Research Unit, Department of Biochemistry and Molecular Biology, University of Southern Denmark (SDU), invites applications as postdoctoral scientist – Denmark 2022

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General Info

Position: Postdoc
No. of Positions: 1
Research Field: , , ,
Joining Date: Apr 01,2022
Contract Period: 3 years
Salary: According to Standard Norms

Workplace:
Mandrup group, Functional Genomics & Metabolism Research Unit
Department of Biochemistry and Molecular Biology (BMB)
University of Southern Denmark (SDU)
Odense, Denmark

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Qualification Details

We are looking for a highly motivated, dedicated, and ambitious candidate with:

  • A PhD degree in Life Science, preferably Molecular Biology, Biomedicine, or Computational Biology
  • Experience with research in the field of transcriptional regulation
  • Documented experience with cell biology and NGS data analysis
  • At least one first-author publication in a relevant journal in the field
  • Strong communication and collaborative skills and a desire to work in an interdisciplinary environment
  • Proficiency in spoken and written English.

Responsibilities/Job Description

According to the lab interest

How to Apply?

Online Application through "Apply Now" Button from this page


Reference Number: -
(If any, use it in the necessary place)

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Documents Required

The application must include the following:• A curriculum vitae including information on previous employment.• A full list of publications stating the scientific publications on which the applicant wishes to rely.

Shortlisting may be used in the assessment process.Incomplete applications and applications received after the deadline will neither be considered nor evaluated.To qualify you must have passed a PhD or equivalent. Applications will be assessed by an expert assessor/committee. Applicants will be informed of their assessment by the university.

Applications must be submitted electronically using the link "Apply online". Attached files must be in Adobe PDF or Word format. Each box can only contain a single file of max. 10 Mb. We strongly recommend that you read How to apply before you apply.Further information for international applicants about entering and working in Denmark.

About the Project

The ability of higher eukaryotic cells to control transcription is a prerequisite for specialization during development, and for maintenance as well as plasticity of cellular identity. It is becoming increasingly clear that this important regulation is dependent on physical compartmentalization of the genome into functional units and on elaborate cooperativity between transcription factors within these units. Understanding the interplay between chromatin topology and transcriptional activity constitutes one of major current challenges in the transcription field. We have recently applied enhancer capture Hi-C to investigate enhancer interactions in human mesenchymal stromal cells (MSCs) undergoing adipocyte differentiation. We showed that enhancers form highly interconnected enhancer communities that appear to act as hubs driving adipocyte lineage determination.In this project, which builds on extensive published and unpublished data from the Mandrup laboratory, we will investigate the interplay between chromatin topology and transcriptional regulation during adipocyte differentiation. These data are expected to have important implications for the understanding of transcriptional regulation in general.

The Functional Genomics & Metabolism Research Unit

The Mandrup Group is located in the Functional Genomics & Metabolism Research Unit, at Department of Biochemistry and Molecular Biology, SDU. The research unit currently hosts seven independent research groups focusing on various aspects of gene regulatory mechanisms controlling cellular identity, differentiation, and metabolism. The research unit constitutes an international, ambitious, highly dynamic, and well-equipped working environment. The unit and the department have state-of-the-art facilities for next generation sequencing, single-cell transcriptomics, flow cytometry, mass spectrometry, metabolomics, bioimaging and transgenic mouse work. Strategic research alliances exist with Odense University Hospital (OUH).

About the Employer: University of Southern Denmark (SDU)

Note or Other details

  • A three-year postdoc position in a stimulating and supportive, international research environment
  • Access to state-of-the-art equipment, facilities, and infrastructure
  • Opportunity to interact with an extensive network of national and international collaborators
  • A competitive salary and social benefits (e.g. health coverage, parental leave, social security etc.)
  • Dedicated assistance and support with various practical, social, and legal aspects (housing, visa, administration, tax etc.), especially for international candidates through our international staff office (ISO) and department.

The successful applicant will be employed in accordance with the agreement between the Ministry of Finance and AC (the Danish Confederation of Professional Associations). Please check links for more information on salary and taxation.


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Contact details

For further information please contact Professor Susanne Mandrup at s.mandrup@bmb.sdu.dk.

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