Postdoc Researcher Position in Umea University, Sweden

Postdoctoral Research Fellowship in Organic Chemistry at Umeå University, Sweden – May

Sweden

Umeå University invites applications for a Postdoctoral fellowship position for a project with a focus on design, organic synthesis and biological evaluation of organic molecules as chemical tools to elucidate the function of metacaspases in plants and protozoa, at the Department of Chemistruy, Sweden – May

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General Info

Position: Postdoctoral position
No. of Positions: 1
Research Field: ,
Deadline to Apply: Expired
Joining Date: ASAP
Contract Period: 2 Years
Salary: 300,000 SEK/Year

Workplace:
Department of chemistry

Umeå University (UMU), Sweden

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Qualification Details

The applicant must hold a PhD degree or a foreign degree that is deemed equivalent in the field of organic chemistry or equivalent. Priority should be given to candidates who have completed their PhD degree no more than three years before the end of the application period, unless special circumstances exist. A candidate who has completed their degree prior to this may be considered if special circumstances exist. Special circumstances include absence due to illness, parental leave or clinical practice, appointments of trust in trade unions or similar circumstances.

Very good command of the English language, both written and spoken, is required. You should have a genuine interest in organic- and medicinal chemistry and be prepared to take on scientific and technical challenges. You should be creative, with good interpersonal and collaborative skills, power of initiative, and a high degree of independence. The applicant must have competence of synthetic organic chemistry (e.g., methodology, total synthesis or medicinal chemistry). Experiences of biochemical and biological evaluations, X-ray crystallography and computational chemistry are merits.

Responsibilities/Job Description

Project description

The objective of the research project is to develop biologically active organic molecules that can be used as chemical tools aimed at meeting the fast-growing demands of basic research in the area of metacaspases (MCs). These enzymes are present in all kingdoms of life, except for animals, and highly selective and specific probes with MC-modulating activity will generate new knowledge regarding the proteases’ structure and function. The results of this project will not only have a transformative impact on the field of MC research but will as well impel large and multidisciplinary community of scientists studying animal caspases. That fact that MCs are found in protozoa but not in humans makes it an attractive target for development of anti-parasitic drugs. Finding inhibitors or activators specific for protozoa MC will not only give valuable insights into the inter-species differences of MC function, but may also be a means of modulating virulence of parasitic protozoa, like Trypanosoma and Leishmania, in mammals thereby reducing their pathogenicity. You will design and synthesize molecules that inhibit or enhance the function of metacaspases by targeting active or allosteric sites. This project will be carried out within a research group that uses multidisciplinary approaches to address medicinal chemistry research questions.

The fellowship covers full-time studies for two years with start as soon as possible. The fellowship amount is SEK 300,000 per year and the project is financed by the Kempe Foundations.

How to Apply?

Application Method: Send Email
Ref. No.: FS 2.1.7-741-22

Application Procedure

A full application should include:

  • Personal letter that summarizes qualifications, research interests, and the reasons for applying for the fellowship,
  • Curriculum vitae with publication list,
  • Certified copy of doctoral degree certificate,
  • Certified copies of other diplomas, list of completed academic courses and grades,
  • Contact information for at least two reference persons

Submit your application as a PDF marked with the reference number FS 2.1.7-741-22, both in the file name and in the subject field of the email, to [email protected]. The application can be written in English or Swedish. Application deadline is 10 May 2022.

About the Department

About the department. The Department of Chemistry at Umeå University is one of the largest departments within the Faculty of Science and Technology and has about 200 employees, of which about 40 are doctoral students, and a strong and expanding research. Three major research areas, Biological Chemistry, Environmental and Biogeochemistry and Technical Chemistry bring together the research of the department and the education in chemistry. We are also a strong partner within KBC Chemical-Biological Center in Umeå. KBC Chemical-Biological Center offers an exciting research environment with excellent resources with regard to research infrastructure.

About the Employer:

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Contact details

For more information, please contact contact Prof. Anna Linusson, phone: 090-786 68 90, email: [email protected].

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