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Postdoctoral Research Fellow in Comparative Physiology, Cell Biology – UiO, Norway

University of Oslo, UiO

Norway

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Nov 10, 2021 23:59 (GMT +1)

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Position as Postdoctoral Research Fellow available in project “Epigenetic mechanisms and cell-type specific gene expression during anoxia and re-oxygenation in crucian carp brain”, funded by the Research Council of Norway at the Department of Biosciences (IBV), University of Oslo, Norway

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General Info

Position: Postdoctoral Research Fellow
No. of Positions: 1
Research Field: ,
Deadline to Apply: November 10, 2021(GMT +1)
Joining Date: ASAP
Contract Period: 3 Years
Salary: 534 400 – 615 800 NOK/Year

Workplace:
Department of Biosciences
University of Oslo i
University of Oslo, UiO
Oslo,

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Qualification Details

The Faculty of Mathematics and Natural Sciences has a strategic ambition is to be among Europe’s leading communities for research, education and innovation. Candidates for these fellowships will be selected in accordance with this, and expected to be in the upper segment of their class with respect to academic credentials.

  • Applicants must hold a degree equivalent to a Norwegian doctoral degree in physiology, cell biology, molecular biology, or a related field. Doctoral dissertation must be submitted for evaluation by the closing date. Only applicants with an approved doctoral thesis and completed defence are eligible for appointment.
  • Fluent oral and written communication skills in English is required
  • Basic practical experience with command-line work (unix, R, etc.) is required
  • Basic practical experience with bioinformatics and processing of large sequencing datasets is required
  • Practical experience with basic molecular biology methods and laboratory practices is required
  • A strong background in comparative physiology or organismal biology is highly desired
  • Experience with whole-animal experiments (and FelasaC-equivalent certification) is highly desired
  • Basic practical experience with isolation of cells is desired
  • Previous research and interest in themes related to the project is desirable (anoxia/hypoxia tolerance, transcriptomics)

Personal skills

  • Ability to design, plan, interpret original experiments in an independent and innovative way
  • Ability and willingness to collaborate and co-author work with other members of the research group, when appropriate
  • Strong motivation for project management and scientific writing
  • Personal suitability and motivation for the position

Responsibilities/Job Description

The task for the postdoctoral fellow will be to carry out single-cell sequencing and characterization of differential gene expressions patterns in different cell types of the crucian carp brain. This includes exposing crucian carp to anoxia in the lab, harvesting viable cells from the brain, prepare single-cell RNA libraries using the 10x Genomics chromium controller and kits, and perform the necessary bioinformatical processing and analysis.

The main project is led by Associate Professor Sjannie Lefevre from the Section for Physiology and Cell Biology (IBV), and collaborators include Dr. Sissel Jentoft from the Centre for Ecological and Evolutionary Synthesis (IBV) and Associate Professor Shuo-Wang Qiao from Department of Immunology at the Institute of Clinical Medicine (Faculty of Medicine). The postdoctoral researcher will be part of the comparative physiology group, and will be expected to collaborate with other members of the group, and take part in supervision of master students.

The main purpose of a postdoctoral fellowship is to provide the candidates with enhanced skills to pursue a scientific top position within or beyond academia. To promote a strategic career path, all postdoctoral research fellows are required to submit a professional development plan no later than one month after commencement of the postdoctoral period.

How to Apply?

Online Application through "Apply Now" Button from this page or from advertisement webpage (URL below)

Reference Number: -
(If any, use it in the necessary place)

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Documents Required

How to apply

The application must include

  • Cover letter (statement of motivation, summarizing scientific work and research interest)
  • CV (summarizing education, positions, pedagogical experience, administrative experience and other qualifying activity)
  • Copies of educational certificates, academic transcript of records
  • A complete list of publications and up to 5 academic works that the applicant wishes to be considered by the evaluation committee
  • Names and contact details of 2-3 references (name, relation to candidate, e-mail and telephone number)

The application with attachments must be delivered in our electronic recruiting system. Foreign applicants are advised to attach an explanation of their University's grading system. Please note that all documents should be in English (or a Scandinavian language).

About the Project

The position is part of the larger project “Epigenetic mechanisms and cell-type specific gene expression during anoxia and re-oxygenation in crucian carp brain”, funded by the Research Council of Norway and placed at the Department of Biosciences (IBV). The crucian carp (Carassius carassius) is a champion when it comes to surviving without oxygen, and much is known about the physiological mechanisms involved. However, molecular mechanisms regulating the physiological responses are unexplored. Preliminary research has indicated that many thousands of genes change their expression in the brain in response to anoxia and re-oxygenation. The magnitude of this transcriptional response has led us to hypothesise that the response may differ between cell types and brain areas.

About the Department

Department of Biosciences (IBV) is one of nine departments at the Faculty of Mathematics and Natural Sciences. Research in the department is organised in five sections covering topics within biochemistry, molecular biology, physiology, cell biology, genetics, aquatic biology, toxicology, ecology, and evolutionary biology. Education across these topics is offered for around 350 bachelor, 250 master, and 120 PhD students. With 52 permanent professors/associate professors, post-docs, researchers, technical, and administrative personnel, the Department has a total staff of 340 from more than 30 different countries. The Department aims to maintain high international standards within both research and teaching. The new bachelor program in bioscience is the first of its kind to include programming and computational modelling as core elements.

About the Employer: University of Oslo, UiO

Note or Other details

Please see the guidelines and regulations for appointments to Postdoctoral fellowships at the University of Oslo.

The University of Oslo has an agreement for all employees, aiming to secure rights to research results a.o.

We offer

  • salary NOK 534 400 – 615 800 per annum depending on qualifications in position as Postdoctoral Research Fellow (position code 1352)
  • a professionally stimulating working environment
  • attractive welfare benefits and a generous pension agreement, in addition to Oslo’s family-friendly environment with its rich opportunities for culture and outdoor activities
  • research training in yeast research, evolutionary biology, bioinformatics, multiomic data generation/integration and machine learning models
  • postdoctoral development programmes

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Contact details

For further information please contact: Sjannie Lefevre, phone: +47 48 36 47 45, e-mail: s.l.nilsson@ibv.uio.no.

For questions regarding the recruitment system, please contact HR adviser Nina Holtan, e-mail: nina.holtan@mn.uio.no.

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