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Postdoc Job in Tumor Biology and Immunology at The Netherlands Cancer Institute, Netherlands

The Netherlands

Postdoc Job in Tumor Biology and Immunology is available for doctoral degree candidates in cell biology and molecular biology/immunology at Group of Leila Akkari, Division of Tumor Biology and Immunology, The Netherlands Cancer Institute, Netherlands 2022

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General Info

Position: Postdoc
No. of Positions: 1
Research Field: , ,
Deadline to Apply: Expired
Joining Date: May 2022
Contract Period: 2 Years
Salary: €3.695,- to € 4.391,- per month

Group of Leila Akkari, Division of Tumor Biology and Immunology

The Netherlands Cancer Institute, NKI


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Qualification Details

We are looking for a talented and enthusiastic scientist who is interested in a dynamic and ambitious environment at a top research institution. Her/his role will be to explore the evolution of immune cells in brain tumors in order to apply rational combinatorial strategies of standard of care treatment with immunotherapy. The successful candidate must have, or be expecting, a Ph.D. in cell and molecular biology/immunology with strong immunology background and hands on animal handling expertise and have published in peer-reviewed journals. She/he will be able to effectively communicate scientific ideas, foster collaboration and have a demonstrable capability for independent thinking. Experience with mouse models of cancer, ideally in immunological research areas, is required. Interested applicants should submit an electronic copy of their CV, the names and contact information of three referees, and a cover letter describing past research experience, current research interests and career goals.

State-of-the-art facilities: The research groups at the NKI are supported by state-of-the-art equipment and facilities, most with dedicated support staff. The Institute has a large mouse facility with special units for transgenesis, intervention studies, pathology and functional imaging, a genomics facility, a functional screening facility for RNAi and small-molecule libraries, excellent facilities for microscopy, flowcytometry, protein expression and purification, and many more.

Inspiring international atmosphere: Approximately 700 people work in the research laboratory and many of the clinicians are involved in research. Work discussions, lectures and seminars are in English and a large number of non-Dutch post-docs, students and staff members contribute to the stimulating and international atmosphere of the Institute.

Responsibilities/Job Description

The Netherlands Cancer Institute (NKI) is an independent research institute located in the lively city of Amsterdam. The Institute covers all major areas of molecular and cellular cancer biology, with special emphasis on mouse tumor models, immunology, functional screens, cancer cell biology and translational research. The Netherlands Cancer Institute and the Antoni van Leeuwenhoek Hospital form an integrated cancer center, combining a research laboratory and a hospital under one roof in a single, independent organization. All hospital departments have an extensive research program, often in close collaboration with the research laboratory. This research is focused on improving cancer treatment through imaging and molecular diagnostics, new medicine, immunotherapy, improved operating techniques, more effective radiotherapy, and combinations of these, epidemiology and psychosocial research.

The Akkari lab and Borst lab are seeking a talented and enthusiastic individual to investigate the interaction between the tumor microenvironment and therapy resistance.

Postdoctoral position available starting in May 2022 in the group of Leila Akkari, Division of Tumor Biology and Immunology at the NKI (Amsterdam, NL) and co-supervised by Dr Gerben Borst, consultant at the Christie NHS Foundation Trust (Manchester, UK). The appointment is for a period of at least 2 years.Leila Akkari´s research group studies the microenvironment-mediated mechanisms of tumor maintenance and therapeutic resistance to conventional therapy in brain malignancies. In particular, we investigate the acquired resistance mechanisms resulting from alterations in the activation and recruitment of myeloid cells and their mediators in response to standard of care treatment in brain tumors, including radiotherapy, surgery and immunotherapy. Our research aims to identify the vulnerabilities in the cancer cell/ stromal compartment heterotypic communication in solid tumors that may be targeted therapeutically.Our research interests involve the use of in vitro and in vivo systems for the study of brain cancer, including sophisticated imaging, as well as transgenic, cell-tracing mouse models and patients sample analyses.The ultimate goal of our projects is to improve the understanding of the complexity of the tumor microenvironment to harness its potential, using the brain as an experimental settings of cancer inflammation.

How to Apply?

Application Method: Online Application
Ref. No.: -

Application Procedure

Interested applicants should submit an electronic copy of their CV, the names and contact information of three referents (add this information in your cover letter) , and a cover letter describing past research experience, current research interests and career goals. We invite everyone who wants to contribute to join us, regardless of ethnicity, nationality, gender, religion, age, or ability.

About the Employer:

Note or Other details

You will join an international research team in a stimulating and interactive research environment. You will be employed for a period of at least 2 years. The gross salary for a fulltime appointment will range from€3.695,- to € 4.391,- per month, depending on previous experience. The terms of employment will be in accordance with FWG 55 of the CAO Ziekenhuizen (Collective Labour Agreement for Hospitals).In addition you will receive a fixed end-of-year bonus in December (8,33%) and in May you will receive 8,33% holiday pay. For more information in regard to the secondary conditions please visit our website: https://www.nki.nl/careers-study/how-to-apply/

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Contact details

For further information visit our home page (www.akkarilab.com) or contact Gerben Borst or Leila Akkari at BORST, Gerben (THE CHRISTIE NHS FOUNDATION TRUST) [email protected][email protected]At the NKI, we value an inclusive environment.

Carly DeSantis, Recruiter +31 6 34511613 [email protected]

Leila Akkari, Group leader [email protected]

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