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PhD studies in Physical Chemistry – Stockholm, Sweden – Nov 2021

Stockholm University (SU)

Sweden

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Nov 5, 2021 23:59 (GMT +2)

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Department of Materials and Environmental Chemistry (MMK) seeks PhD student in Physical Chemistry at the Faculty of Natural sciences, Stockholm University – Sweden, Nov 2021.

Project title: Developing electron crystallographic methods to probe 3D atomic structures and charges in metalloproteins and enzymes.

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General Info

Position: PhD
No. of Positions: 1
Research Field:
Deadline to Apply: November 5, 2021(GMT +2)
Joining Date: -
Contract Period: Not Mentioned
Salary: According to Standard Norms

Workplace:
Faculty of Natural Sciences
Department of Materials and Environmental Chemistry (MMK)
Stockholm University (SU)
Stockholm,

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Qualification Details

In order to meet the general entry requirements, the applicant must have completed a second-cycle degree, completed courses equivalent to at least 240 higher education credits, of which 60 credits must be in the second cycle, or have otherwise acquired equivalent knowledge in Sweden or elsewhere.

In order to meet the specific entry requirements, the general syllabus for doctoral studies in the field of Chemistry is valid. Those studies should include at least one specialized course or a thesis in the research subject. In order to facilitate the evaluation of merits and suitability for the PhD studies your curriculum vitae (CV) should contain information about the extent and focus of the academic studies. The quantity (as part of an academic year) and the quality mark of courses in chemistry and physics are of particular interest. Please, state titles of undergraduate theses and project works.

The qualification requirements must be met by the deadline for applications.

SelectionThe selection among the eligible candidates will be based on their capacity to benefit from the training. The following criteria will be used to assess this capacity: the candidates’ documented knowledge in a relevant field of research, written and oral proficiency in English, the capacity for analytical thinking, the ability to collaborate, as well as creativity, initiative, and independence. The assessment will be based on previous experience and grades, the quality of the degree project, references, relevant experience, interviews, and the candidate’s written motivation for seeking the position.

A short list will be set up and interviews with the top candidates will be carried out at the department or via internet.

Admission Regulations for Doctoral Studies at Stockholm University are available at: www.su.se/rules and regulations.

Responsibilities/Job Description

According to the lab interest

How to Apply?

Online Application through "Apply Now" Button from this page or from advertisement webpage (URL below)

Reference Number: -SU FV-3398-21
(If any, use it in the necessary place)

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Documents Required

Please include the following information with your application

  • Your contact details and personal data
  • Your highest degree
  • Your language skills
  • Contact details for 2–3 references

and, in addition, please include the following documents

  • Cover letter
  • CV – degrees and other completed courses, work experience and a list of degree projects/theses
  • Project proposal/Research proposal describing:– why you are interested in the field/project described in the advertisement– what makes you suitable for the project in question%]
  • Degree certificates and grades confirming that you meet the general and specific entry requirements (no more than 6 files)
  • Letters of recommendation (no more than 6 files)
  • Degree projects/theses (no more than 6 files).

The instructions for applicants are available at: How to apply for a position.

About the Department

The Department of Materials and Environmental Chemistry (MMK) is, with about 160 employees, one of the largest departments at the Faculty of Natural sciences at Stockholm University. A significant part of the teaching activities is at the undergraduate level with courses in General, Physical, Inorganic, and Analytical Chemistry. The teaching at the graduate level focuses on the master programs in Sustainable Chemistry and Analytical Chemistry. Research activities of MMK focus primarily on materials, and include different classes such as ceramics, glasses, self-assembled, porous materials, and soft matter. The projects often encompass synthesis, and characterization by X-ray, neutron diffraction, electron microscopy, solid-state NMR, and computer modelling of materials with a potential for various applications. Research activities in the area of Analytical Chemistry focus on developing advanced analytical techniques for studies of organic compounds and biomolecules.

About the Project

Knowing the 3D atomic structures is crucial for understanding the functions of macromolecules and chemical processes in biological systems. X-ray crystallography is presently the most important technique for structure determination of macromolecules but it requires large crystals and cannot determine the charges of individual atoms. In addition, it cannot determine the charges of individual atoms, which is crucial for understanding the redox chemistry in enzymes. During the past decade, electron diffraction has undergone a tremendous development into 3D electron diffraction (3D ED), also known as MicroED. It has shown to be powerful in determining atomic structures from nano- and microcrystals too small for X-ray crystallography.

The PhD project aims at developing and applying new 3DED/MicroED methods to determine 3D atomic structures and charge states in metalloproteins and enzymes. The main tasks of the PhD candidate will be to develop crystallization protocols to obtain suitable microcrystals for 3DED/MicroED, optimize EM sample preparation, use advanced cryo-electron microscopic techniques for data collection and data analysis. The candidate will apply the new methods to determine 3D structures as well as charge states for metals and amino acids in metalloproteins/ enzymes and their catalytic intermediates.

The student will be part of a large group and in close collaboration with researchers at Department of  Biochemistry and Biophysics, SU and other universities. She/he should have a strong collaborative and communication skill, be self-motivated and a good team player. The applicant should also have excellent skills in the English language, both written and spoken. Good knowledge on protein crystallization, biochemistry, structural biology, crystallography, TEM, data analysis is desired but not necessary. The candidate should have a Master or equivalent degree in Chemistry, Biochemistry, or Chemical Engineering. The student will work within the project “Electron crystallographic methods to probe 3D atomic structures and charge states in macromolecules” funded by the Knut & Alice Wallenberg foundation.  Further information can be found at https://kaw.wallenberg.org/en/xiaodong-zou and https://www.su.se/english/profiles/xzou-1.187418

About the Employer: Stockholm University (SU)

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Contact details

For more information, please contact the PI (xzou@mmk.su.se). For general information about the Department of Materials and Environmental Chemistry, please contact the Head of the Department, Professor Gunnar Svensson, gunnar.svensson@mmk.su.se.

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