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PhD Studies – Gene editing and cell-based therapy, Molecular Biology – Norway

University of Oslo, UiO


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Nov 1, 2021 23:59 (GMT +1)

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PhD Studies – gene editing and cell-based therapy, Molecular Biology is available at the Institute of Clinical Medicine, Division of Cancer Medicine, University of Oslo – Norway, Nov 2021

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General Info

Position: PhD
No. of Positions: 1
Research Field:
Deadline to Apply: November 1, 2021(GMT +1)
Joining Date: -
Contract Period: 3 Years
Salary: NOK 491 200 – NOK 534 400 per annum

Institute of Clinical Medicine
Division of Cancer Medicine
University of Oslo, UiO

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Qualification Details

  • MD or MSc (or equivalent) in relevant topic
  • Ability to design, plan, and execute experiments
  • Experience in molecular biology techniques such as cell culturing, cloning, qPCR, ELISA, Western blotting, Immunohistochemistry (requirement)
  • Formal accreditation (FELISA C or similar) and experience working with mice models is an advantage
  • Experience with CRISPR gene editing, stem cell work, and in vivo transplants is an advantage
  • Proficient in English language, both written and oral.

For applicants who have yet to receive their Master’s degree, the Master’s thesis must have been submitted for evaluation before the application deadline. Such applicants should note the date of submission of their Master’s degree in the cover letter. Appointment is dependent on the master thesis being approved. The candidate will admit to the PhD program at the Faculty of Medicine  (see How to apply for admission to the PhD programme - Faculty of Medicine ( for requirements).

Personal skills

  • Excellent communication and team working skills
  • Organized and structured
  • Flexible
  • Enthusiastic and willing to learn new methods and techniques

When evaluating the application, emphasis will be given to the applicant’s academic and personal prerequisites to carry out the project.

Applicants may be called in for an interview.

Responsibilities/Job Description

The research group has conducted basic, translational and clinical research for more than 30 years, with a focus on blood coagulation factors and their role in disease.

How to Apply?

Online Application through "Apply Now" Button from this page or from advertisement webpage (URL below)

Reference Number: -
(If any, use it in the necessary place)

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Documents Required

The application must include:

  • Cover letter (statement of motivation, summarizing scientific work and research interest).
  • CV (summarizing education, positions, pedagogical experience, administrative experience and other qualifying activities).
  • Copies of educational certificates (academic transcripts only).
  • Any research publications that the applicant wishes to be considered.
  • List of reference persons: 2-3 references (name, relation to candidate, e-mail and phone number).

The application with attachments must be delivered in our electronic recruiting system, please follow the link “apply for this job”. Foreign applicants are advised to attach an explanation of their University's grading system. Please note that all documents should be in English (or a Scandinavian language).

About the Position

In the project, you will work on a bleeding disorder called inherited factor (F) VII deficiency. FVII is a vital protein in the blood coagulation process and an inherited deficiency of this protein is caused by mutations in the F7 gene leading to severely reduced activity of the FVII protein in the blood. Clinically, these patients experience frequent and sometimes severe bleeding episodes, and the only treatment today is replacement therapy that is expensive and invasive. We are using CRISPR gene editing and advanced cell reprogramming techniques to correct the mutation in the patients’ own cells and establishing transplant procedures in mice models to restore FVII activity and function. These important pre-clinical studies will lay the foundation for cell-based therapies in patient with FVII deficiency.

You will work closely with an experienced researcher and a postdoctoral fellow on the project. The position is over a three-years period.

The research fellow must take part in the Faculty’s approved PhD program and is expected to complete the project within the set fellowship period. The main purpose of the fellowship is research training leading to the successful completion of a PhD degree.

About the Employer: University of Oslo, UiO

Note or Other details

Please see the guidelines and regulations for appointments to Research Fellowships at the University of Oslo.

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Contact details

Project leader, professor Per Morten Sandset  email:

Researcher, Maria Eugenia Chollet Dugarte email:

Questions regarding the online application form can be directed to Senior HR Adviser Thoril Kristiansen email:

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