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PhD position – Studying bacterial infection in organoid models (19639) – University of Lausanne, Switzerland, 2022

Switzerland

PhD position is available to use novel human organoid models to study P. aeruginosa infections and the influence of the innate immune system on infection outcome and drug treatment at National Center of Competence in Research (NCCR), University of Lausanne, Switzerland, 2022

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General Info

Deadline to Apply: Expired
Position: PhD position
Fellowship/Scholarship:
No. of Positions: 1
Eligibility (Gender):
Eligibile Nationals: All Nationals
Research Field: , , , , ,
Joining Date: Aug 01, 2022
Contract Period: 1 year, renewable, maximum 4 years

Workplace:
National Center of Competence in Research (NCCR)

University of Lucerne (UNILU), Switzerland
,

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Qualification Details

We are looking for a highly motivated and talented PhD student. A Master degree in biology, immunology, biochemistry, bioengineering, or a similar discipline is required. The optimal candidate has basic knowledge in microscopy, cell biology and infection biology as well as excellent communication and teamwork skills.

Responsibilities/Job Description

The PhD student will occupy a bridging position between the Broz and Jenal labs, and will be embedded in both groups at the Universities of Basel and Lausanne during the different phases of the project. During the project the candidate will receive training in microbiology and human mimetic models, followed by training in immunology and gene expression analysis; and engage in different projects and collaborations within the NCCR network.

How to Apply?

Application Method: Online Application
Ref. No.: 19639

Application Procedure

The application should include a brief personal statement, explaining how your qualifications and experience relate to the role, together with a full, up-to-date CV and at least two reference letters. Review of applications will start immediately. Please note that only online applications will be considered. Shortlisted candidates will be informed as soon as possible about the interview procedure

Please, send your full application in Word or PDF. Only applications through this website will be taken into account.

About the

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About the Department/Section/Group

The National Center of Competence in Research (NCCR) AntiResist is a Swiss-wide research consortium funded by the Swiss National Science Foundation (SNSF). AntiResist aims to tackle the global spread of antibiotic resistance, a problem of strategic national and international importance. To reach this goal, AntiResist has assembled an interdisciplinary group of experts in the fields of clinical research, infection biology, chemistry, computation, engineering and pharmacology. to study bacterial infection and the response to antibiotics by an integrated approach “from bedside to bench and back again”. NCCR AntiResist aims to revitalize antibiotic R&D with an integrated “bedside to bench and back” approach and to train the next generation of researchers and clinicians in infectious diseases using state-of-the-art technology.

Pseudomonas aeruginosa is a major cause of life-threatening hospital infections, including pneumonia, septicemia, burn and wound infections. Acute and chronic P. aeruginosa infections are associated with significant mortality, and immunocompromised people and cystic fibrosis (CF) patients are at particular risk. The steady rise of antibiotic resistance creates an urgent need for the development of novel anti-pseudomonal treatment strategies.

The goal of the joint PhD project between the groups of Petr Broz (Dept. of Immunobiology, University of Lausanne) and Urs Jenal (Biozentrum, University of Basel) is to use novel human organoid models to study P. aeruginosa infections and the influence of the innate immune system on infection outcome and drug treatment.

About the Employer: University of Lucerne (UNILU), Switzerland

Note or Other details

The student will enroll in the PhD program in Cancer and Immunology of the University of Lausanne and the position will be funded for up to 4 years. The Broz and Jenal labs offer a highly interactive, interdisciplinary and international environment, with the mission to understand the innate immune response of human tissue to bacterial infections (Broz lab), and to uncover mechanisms of bacterial virulence and persistence (Jenal lab). As a member of the highly dynamic Swiss-wide NCCR network AntiResist, the PhD student will profit from regular interactions with different scientific disciplines, a large array of educational events, meetings and courses, and broad mentorship from leading scientists in the field.

The expertise of the labs covers cutting-edge techniques in the fields of molecular biology, microbiology, immunology, cell death signaling and cell biology. Both the Department of Immunobiology of the University of Lausanne and the Biozentrum of the University of Basel offer excellent internal support from various state-of-the-art core facilities with expert staff. In the frame of NCCR AntiResist network (https://www.nccr-antiresist.ch/en/) we collaborate closely with researchers with complementary expertise, including clinicians, bioengineers, chemists and computational scientists.


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Contact details

Prof. Petr Broz
[email protected]
tel: +41 21 692 55 56

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