PhD Position SDU University of Southern Denmark

PhD Position in Life Science, Molecular Biology, Biomedicine – SDU, Denmark, 2022

Denmark

The Mandrup group at the Functional Genomics & Metabolism Research Unit, Department of Biochemistry and Molecular Biology, University of Southern Denmark, invites applications from outstanding candidates who are interested in joining our group as a PhD student at Denmark – 2022

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General Info

Position: PhD
No. of Positions: 1
Research Field: ,
Deadline to Apply: Expired
Joining Date: Aug 01, 2022
Contract Period: 3 Years
Salary: According to standard norms

Workplace:
Department of Biochemistry and Molecular Biology

University of Southern Denmark (SDU)

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Qualification Details

We are looking for highly motivated, dedicated, and ambitious candidates with:

  • A Master’s degree in Life Science, preferably Molecular Biology, Biomedicine, or Computational Systems Biology. The degree must be completed by the start of the PhD scholarship.
  • Experience with cell biology or NGS data analysis. Competence in adipose tissue biology, immunology, advanced microscopy, or transcriptional regulation would be an advantage.
  • Strong communication and collaborative skills and an interest in working in an interdisciplinary environment.
  • Proficiency in spoken and written English.

Responsibilities/Job Description

In a new project recently funded by the Health Insurance “danmark” we shall together with Assistant Professor Søren Fisker Schmidt investigate the mechanisms underlying the so-called healthy obesity associated with lower body fat deposition. We will use advanced single cell sequencing techniques, combined with spatial transcriptomics and a range of mechanistic follow-up studies to determine the cellular and molecular differences between fat biopsies from the abdominal and hip regions of people with apple- and pear-shaped obesity. Biopsies will be obtained through a close collaboration with Fredrik Karpe, professor at University of Oxford and director of the Oxford Biobank. Insight from this project will help the identification of key transcriptional and signalling mediators causally associated with healthy (and unhealthy) adipose tissue that can be explored therapeutically with the aim to prevent development of obesity comorbidities.

How to Apply?

Application Method: Online Application
Ref. No.: -

Application Procedure

Application must be in English and include the following:

  • A research proposal/description of your approach to the above project (max one page excluding references).
  • A letter stating your specific interests, motivation and qualifications for the project (max. two pages) (please attach this under box "Application form").
  • Detailed CV, including personal contact information, education, work/research experience and skills relevant for the position, publications/manuscripts.
  • Copies of diplomas, bachelor as well as Master’s degree, including transcript of notes/grades. If awaiting Master’s diploma, provide a written statement from the supervisor.
  • At least two signed reference letters. Should your referees wish to send their letters directly to us, please have them use e-mail: [email protected] mentioning your name and the title of the position in the subject line. And please note that these also need to reach us before deadline.

 

About the Department/Section/Group

The Mandrup Group

The Mandrup Group has a long-standing interest in understanding the molecular crosstalk between transcriptional regulation and metabolism in adipocytes and pancreatic β-cells and to understand the molecular basis for the plasticity of cells in the adipose tissue and endocrine pancreas. We also have a long-time interest in the transcriptional network regulating lineage determination and differentiation of adipocyte progenitors. Our laboratory combines genome-wide studies of factor binding, epigenetic marks, and chromatin structure with detailed molecular analyses of the crosstalk between transcriptional regulators. We run an inhouse sequencing platform including single cell sequencing and bioinformatic pipeline.Susanne Mandrup is Director of Center of Excellence in Functional Genomics and Tissue Plasticity (ATLAS) and Center of Adipocyte Signaling (ADIPOSIGN).

The Schmidt Group

Research in the Schmidt Group focuses on  transcriptional coordination of macrophage diversity and plasticity in metabolic health and disease. For this, we combine single cell analyses of clinical samples, cell culture studies, and viral targeting strategies in animal disease models. As a member of ATLAS, a key research focus in the group is understanding cellular diversity and communication determining differential interindividual phenotypic outcomes of obesity.

About the Employer:

Note or Other details

Appointment as a PhD Research Fellow is for three years. Employment stops automatically at the end of the period. The holder of the scholarship is not allowed to have other paid employment during the three-year period.

The successful applicant will be employed in accordance with the agreement on salaried PhD scholars between the Ministry of Finance and AC (the Danish Confederation of Professional Associations). Please check links for more information on salary and taxation.

The successful candidate will be enrolled at this university in accordance with faculty regulations and the Danish Ministerial Order on the PhD Programme at the Universities (PhD order).

Further information for international applicants about entering and working in Denmark.

  • A three-year PhD position in a highly stimulating, supportive, international, and interdisciplinary research environment.
  • Enrollment in the PhD school of Biochemistry and Molecular Biology, which allows the candidate to tailor a flexible individualized course programme.
  • Training in a wide range of skills including research management, communication, networking, presentations, writing of manuscripts etc..• Research exchange to collaborating institution, depending on the interest of the PhD fellow.
  • Mentoring and career development.
  • Access to state-of-the-art equipment, facilities, and infrastructure.• Opportunity to interact with an extensive network of national and international collaborators.
  • A competitive salary and social benefits (e.g. health coverage, parental leave, social security etc.).
  • Dedicated assistance and support with various practical, social, and legal aspects (housing, visa, administration, tax etc.), especially for international candidates through our international staff office (ISO) and department.

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Contact details

For further information please contact Professor Susanne Mandrup, tel.: +45 6550 2340, e-mail: [email protected].

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