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Phd Position in Biocatalysis, Biotechnology – UvA, The Netherlands

University of Amsterdam (UvA)

The Netherlands

Faculty of Science, Van ‘t Hoff Institute for Molecular Sciences offers PhD Position is available for a project in the area of biocatalysis, bio-organic chemistry and biotechnology – University of Amsterdam, The Netherlands – Oct 2021.

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General Info

Position: PhD
No. of Positions: 1
Research Field: , ,
Deadline to Apply: Expired
Joining Date: -
Contract Period: 4 Years
Salary: €2,434 to €3,111 gross per month

Faculty of Science
Van ‘t Hoff Institute for Molecular Sciences
University of Amsterdam (UvA)

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Qualification Details

Candidates must hold a Master’s diploma in chemistry or biotechnology or a cognate discipline. The ideal PhD candidate should have theoretical knowledge and some hands-on experience in one or more of the following sub-disciplines: - biocatalyis and biotransformations; - enzyme engineering (incl. computational/structural analysis of proteins); - synthetic organic chemistry; - standard cloning techniques of molecular biology; - analysis of biochemical reaction via GC/HPLC.

The ability to collaborate and adapt in an international team is of utmost importance, and candidates must possess good communication skills in oral and written English.

Responsibilities/Job Description

The project comprises the following tasks: (i) the engineering of novel enzymes to improve existing catalytic activity, or expand substrate scope or tune chemical selectivities; (ii) the further utilisation of these enzymes into multi-enzymatic reactions aimed at the conversion of renewable building blocks into chiral amines and amino alcohols; (iii) the testing of the cascade reactions through the co-expression of the enzymes in a microbial strain and biotransformations in vivo, or through the use of immobilised enzymes in flow systems; (iv) write periodic scientific reports, manuscripts and a PhD thesis.

This project will be developed in synergy with already existing projects in the biocatalysis group, dealing with enzymatic degradation of renewable starting material or synthetic polymers and the asymmetric synthesis of amines.

How to Apply?

Online Application through "Apply Now" Button from this page or from advertisement webpage (URL below)

Reference Number: -21-744
(If any, use it in the necessary place)

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Documents Required

Applications in .pdf should include:

  • a motivation letter and CV, including a list of publications,

The selection process commences immediately, and it will close when a suitable candidate has been found, even if this is prior to the final date of the application window.

About the Department

The Faculty of Science has a student body of around 7,000, as well as 1,600 members of staff working in education, research or support services. Researchers and students at the Faculty of Science are fascinated by every aspect of how the world works, be it elementary particles, the birth of the universe or the functioning of the brain.

The Van 't Hoff Institute for Molecular Sciences (HIMS) is one of eight institutes of the University of Amsterdam (UvA) Faculty of Science. HIMS performs internationally recognized chemistry and molecular research, curiosity driven as well as application driven. This is done in close cooperation with the chemical, flavor & food, medical and high-tech industries. Research is organized into four themes: Synthesis & Catalysis, Analytical Chemistry, Computational Chemistry and Molecular Photonics.

The Biocatalysis group is headed by Dr. Francesco Mutti. In general, the Biocatalysis group carries out cutting-edge research at the interface between chemical and biological sciences. The research mainly focuses on the development of novel biocatalysts for the sustainable synthesis of high-value chemical products as well as for the degradation and recycling of waste materials. Complementary research lines are the identification and characterization of novel enzymes, the engineering of novel enzymes and the application of enzymes in cascades reactions in vitro (in batch or in flow) and in vivo.

About the Employer: University of Amsterdam (UvA)

Note or Other details

A temporary contract for 38 hours per week, preferably starting on 1 November or 1 December 2021, for the duration of four years (the initial contract will be for a period of 18 months and after satisfactory evaluation it will be extended for a total duration of four years). This should lead to a dissertation (PhD thesis). We will draft an educational plan that includes attendance of courses and (international) meetings. We also expect you to assist in teaching undergraduates and master students.

The salary, depending on relevant experience before the beginning of the employment contract, will be €2,434 to €3,111 (scale P) gross per month, based on a fulltime contract (38 hours a week). This is exclusive 8 % holiday allowance and 8.3% end-of-year bonus. A favourable tax agreement, the ‘30% ruling’, may apply to non-Dutch applicants. The Collective Labour Agreement of Dutch Universities is applicable.

Are you curious about our extensive package of secondary employment benefits like our excellent opportunities for study and development? Take a look here.

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Contact details

Do you have questions about this vacancy? Or do you want to know more about our organisation? Please contact:

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