PhD Position in UCPH University of Copenhagen Denmark

PhD fellowship in phage-microbiome interactions at the GLOBE Institute, UCPH, Denmark, May 2022

Denmark

We are looking for a highly motivated and dynamic candidate to fill a 3-year PhD studentship to work on the role of the bacteriophage-host interactions in different fish species at the Center for Evolutionary Hologenomics, GLOBE Institute, University of Copenhagen. The position will start on 1 August 2022, or as soon as possible thereafter.

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General Info

Position: PhD Fellowship
No. of Positions: 1
Research Field:
Deadline to Apply: Expired
Joining Date: 1st August 2022
Contract Period: 3 Years
Salary: 28,300 DKK/Roughly 3,800 EUR

Workplace:
Center for Evolutionary Hologenomics, GLOBE Institute

University of Copenhagen (UCPH), Denmark

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Qualification Details

Applicants must have qualifications corresponding to a master’s degree related to the subject area of microbiology with focus on bacteriophage – bacteria interactions in marine environments, including data analyses and interpretation of evolutionary genomics and microbiome data. In this regard they must have demonstrable expertise with experimental phage biology (phage isolation, PFU assays, qPCR, CRISPR modifications) and marine fish systems, DNA extractions and generation of NGS based sequence data. Additionally, experience with preparation and analysis of NGS data in command line base bioinformatics pipelines is also preferred.

Other important criteria are:

  • The grade point average achieved
  • Professional qualifications relevant to the PhD project
  • Previous publications
  • Relevant work experience
  • Other professional activities including international experience
  • Curious mind-set with a strong interest on phage data in the context of hologenomics.
  • Language skills.

Responsibilities/Job Description

Project description

It has become clear that the gut microbiome shapes the phenotype of vertebrate hosts, with profound consequences for phenotypic traits related to growth and health. However, an often-ignored part of the gut microbiome communities relate to the virome including bacteriophages. Indeed, it has been suggested that the specific bacteriophages may play a larger role than e.g. the surrounding environment, in regulating the composition of the host associated gut microbiome community. This project will add to this knowledge gap by considering various fish model systems to better understand how phages control microbiome dynamics, and if this knowledge can ultimately be transferred into concrete applied solutions in the food production and human health sectors where there is an interest in modifying microbiomes. The project will include focus on both wild and farmed fish populations and with eye towards longer term potential of translating the results into applied phage therapy solutions. The student is expected to apply a hologenomics approach to study the role of the virome in regulating beneficial microbiome functions. This PhD fellowship will be supervised by Assoc. Prof. Morten Limborg and by Prof. Thomas Sicheritz-Pontén.

Job description

Your key tasks as a PhD student at SUND are:

  • Carry through an independent research project under supervision
  • Complete PhD courses or other equivalent education corresponding to approx. 30 ECTS points
  • Participate in active research environments including a stay at another research team
  • Obtain experience with teaching or other types of dissemination related to your PhD project
  • Teach and disseminate your knowledge
  • Write a PhD thesis on the grounds of your project.

How to Apply?

Application Method: Online Application
Ref. No.: -

Application Procedure

Your online application must be submitted in English by clicking ‘Apply now’ below. Furthermore, your application must include the following documents/attachments – all in PDF format:

  1. Motivated letter of application (max. one page)
  2. CV incl. education, experience, language skills and other skills relevant for the position
  3. Certified copy of original Master of Science diploma and transcript of records in the original language, including an authorized English translation if issued in other language than English or Danish. If not completed, a certified/signed copy of a recent transcript of records or a written statement from the institution or supervisor is accepted. As a prerequisite for a PhD fellowship employment, your master’s degree must be equivalent to a Danish master’s degree. We encourage you to read more in the assessment database: https://ufm.dk/en/education/recognition-and-transparency/find-assessments/assessment-database. Please note that we might ask you to obtain an assessment of your education performed by the Ministry of Higher Education and Science
  4. Publication list (if possible)

The further process

After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor.The assessor makes a non-prioritized assessment of the academic qualifications and experience with respect to the above-mentioned area of research, techniques, skills and other requirements listed in the advertisement.Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

About the Group

The Center for Evolutionary Hologenomics was recently funded by the Danish National Research Foundation to develop and implement state of the art ‘omics and associated computational techniques, to address through experimental and theoretical research, four key themes underscoring life on earth. Specifically, these are: What is the relationship between a host’s genome, or epigenome, and the functional and taxonomic makeup of its associated microbial metagenome? Does this relationship explain ongoing ecological and evolutionary processes in the host? Could this relationship provide an alternate explanation to some of life’s big transitions? And, how have we humans exploited this relationship? The Centre is embedded within the GLOBE Institute, that is part of the Faculty of Health and Medical Sciences at the University of Copenhagen. The Institute’s main purpose is to address basic scientific questions through interdisciplinary approaches. The institute operates at the intersection of natural sciences, medical sciences and the humanities.

About the Employer:

Note

The place of employment is at the GLOBE Institute, Faculty of Health and Medical Sciences, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include laboratories for the preparation of genomic scale datasets from modern and historic materials, as well as computational servers for the analysis of such data.

Depending on seniority, the monthly salary starts at approximately 28,300 DKK/Roughly 3,800 EUR (April 2022 level) plus pension.

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Contact details

Principal supervisor is Assoc. Prof. Morten Limborg, Center for Evolutionary Hologenomics, the GLOBE Institute, Email: [email protected], +45 61 28 29 84

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