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PhD fellowship in Force measurement in cellular adhesions via plasmonics and DNA origami

Aarhus University (AU), Denmark

Aarhus University, Denmark are invited for a PhD fellowship/scholarship at Graduate School of Natural Sciences, within the Nanoscience programme.


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General Info

Position: PhD
Fellowship/Scholarship: Natural Sciences - Aarhus University GSNS PhD Scholarships
No. of Positions: 1
Eligibility (Gender):
Eligibile Nationals: All Nationals
Research Field: , , ,
Joining Date: May, 2022
Contract Period: -

Interdisciplinary Nanoscience Center (iNANO)
Graduate School of Natural Sciences
Aarhus University (AU)
Aarhus C, Denmark

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Qualification Details

Successful applicants to the PhD position must either have a relevant Master’s degree in Nanoscience, Chemistry, Physics or Molecular biology, or equivalent or have completed a bachelor’s degree in Nanoscience, Chemistry, Physics or Molecular biology and be expecting to have completed around 12 months of a 2 years master’s degree relevant for admittance as a 4+4 PhD student. Competences in materials fabrication will be an advantage but not obligatory.

Responsibilities/Job Description

According to the lab interest

How to Apply?

Online Application through "Apply Now" Button from this page

Reference Number: -
(If any, use it in the necessary place)

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Documents Required

Before you apply, please read the application guide thoroughly. You can find the guide here.How to apply:

1)      Find the application form:Go to https://phd.nat.au.dk/for-applicants/apply-here/ - Note, the online application system opens on 1 December 2021.Choose February 2022 Call with deadline 1 February 2022 at midnight (23.59 CET).You will be directed to the call, and must choose the programme “Nanoscience”.

2)      Fill in the following information:

  • Personal information
  • Academic background
  • Admission
  • Financing (if any): Please choose AU funds
  • Study: In the dropdown menu you must choose the project: “Force measurement in cellular adhesions via plasmonics and DNA origami (Fmcavp)”
  • Source (how you found out about the call)

Next to some of the information fields you will find a number. Click on the number to get further directions on how to fill in the information field/what information is needed.

3)      Application attachments:Please be aware that you cannot submit the application if one or several of these documents have not been uploaded.

If you wish to upload more than one document under each section, you must scan/merge all documents into one large PDF file and upload this. Please note that we reserve the right to remove scientific papers, large reports, theses and the like. Instead you can indicate a URL where the information is available.

All information in the application must be in English or Danish, preferably English. A certified English translation is required for documents written in languages other than English or one of the Scandinavian languages (i.e. Norwegian, Swedish or Danish) languages.

As a minimum, all applications must include (pdf-files only, max. 20 MB, and no zip):

  • Curriculum vitae,
  • Motivation (max. 1 page)
  • One reference (template for references)
  • Transcripts, grade point averages (weighted and unweighted), and diploma(s) for both Bachelor’s and Master’s degree. If the original documents are not in English or one of the Scandinavian languages (i.e. Norwegian, Swedish or Danish) then copies of the original documents as well as a certified English translation must be attached.
  • Project description (½-4 pages). For technical reasons, you must upload a project description. When - as here - you apply for a specific project, please simply copy the project description above, and upload it as a PDF in the application. If you wish to, you can indicate an URL where further information can be found. Please note that we reserve the right to remove scientific papers, large reports, theses and the like.
  • Documentation of language skills if required.

After submission of the application, you will receive a confirmation e-mail with an application ID, you should use for reference if needed.

About the Natural Sciences - Aarhus University GSNS PhD Scholarships

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About the Project

The PhD project aims to design and develop a plasmonic DNA origami platform to study molecular interactions between cellular receptors and ligands within adhesion and signalling complexes.

Cells respond to biochemical and mechanical signals from their microenvironment either through interactions with the extracellular matrix or with ligands presented at other cells. Many interactions occur in connection with large adhesion complexes formed by the cell to connect to the ECM (e.g. focal complexes/adhesions or hemidesmosomes) or between cells (e.g. desmosomes or immunological synapse). This project will develop tools to present nanosensors within a cellular adhesion by using patterning tools to pattern ligands and plasmonic readout elements and use them to study force generation for different ligands in cellular signalling complexes.

In our group we have a focus on biointerfacial interactions using plasmonics and patterning as tools to study protein and cellular interactions at the nanoscale. The group is part of the DG center CellPAT which focusses on cellular signalling, this project will benefit from collaborations in that center.

The research approach will be to use patterning approaches such as DNA origami to pattern protein and peptide ligands together with metallic nanoparticles as nanoscale sensors and use them in in vitro cellular systems to study mechanotransduction events.

About the Department

The PhD position is in the Nanobiointerfaces group (nanobiointerfaces.dk) at the iNANO center. The international and interdisciplinary group headed by Professor Duncan Sutherland researches in the area of nanomaterials and nanoscience applied in life science and energy materials.

iNANO, Interdisciplinary Nanoscience Center (www.inano.au.dk), was established in 2002 and at present is a major research and education center based at Aarhus University hosting 60 senior scientists, ~100 PostDocs and ~100 PhD students. The center combines expertise and faculty from Physics, Chemistry, Molecular biology and Medicine to carry out world class interdisciplinary research in Nanoscience and Nanotechnology. The center gives access to a broad range of infrastructure, tools and expertise including clean-room facilities. With a 5 year undergraduate nanotechnology programme and nanoscience graduate programme (www.inanoschool.au.dk) the center provides a full educational environment. In addition to the large base of basic research, the center has a large number of ongoing industrial projects and partnerships.

About the Employer: Aarhus University (AU)

Note or Other details

The graduate school reserves the right to verify the authenticity of your educational diploma and transcripts:

  • Request additional information to verify an application.
  • Reject the application if it is proven, or if the University has reasonable belief, that the information provided is false or if the applicant refuses to provide the requested information, whether or not an offer has already been made.
  • For further information on applying, assessment procedures, etc. please see the GSNS Application Guide.

Please note:

  • The programme committee may request further information or invite the applicant to attend an interview.
  • The project will only be initiated if final funding (from the graduate school/the faculty) is secured.

All interested candidates are encouraged to apply, regardless of their personal background. Aarhus University’s ambition is to be an attractive and inspiring workplace for all and to foster a culture in which each individual has opportunities to thrive, achieve and develop. We view equality and diversity as assets, and we welcome all applicants.

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Contact details

Applicants seeking further information for this project are invited to contact: Professor Duncan Sutherland, Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Gustav Wieds Vej 14, DK-8000,  Aarhus C, Denmark
Mobil tlf.: +45 23385789E-mail: duncan@inano.au.dk

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