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PhD candidate in Pharmacy, Molecular life sciences, Biomedical sciences – Radboudumc

The Netherlands

PhD candidate position is available ‘Pharmacometrics in anti-tuberculosis drug development’, within the department of Pharmacy, at the Radboud university medical center, in the Netherlands, 2022

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General Info

Position: PhD candidate
No. of Positions: 1
Research Field: , ,
Deadline to Apply: Expired
Joining Date: ASAP
Contract Period: 4 Years
Salary: 2570 to 3271 Euro/Month

Department of Pharmacy

Radboud university medical center, the Netherlands


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Qualification Details

We are looking for a highly motivated PhD candidate with good communicative skills. You work independently and accurately and you take responsibility for your findings. In addition, you are a team player who likes to work in a social environment and have the capacity to work under pressure when needed. Although you are part of an international consortium with milestones and deliverables, the project is in its initiation phase for which a creative and flexible mind and working attitude is required.Furthermore, you recognize yourself in the profile below:

  • MSc degree in Pharmacy, Molecular life sciences, Biomedical sciences, Biotechnology or any comparable science.
  • Experience with data analysis and/or programming, skills in R and NONMEM are specifically valuable.

Responsibilities/Job Description

As PhD candidate you will be part of the Pharmacology and Pharmacogenomics work package. You will support development of novel anti-tuberculosis drug regimens through application of pharmacometric modelling. Will you join our team?

  • Contribute to the design of upcoming anti-tuberculosis drug studies by performing clinical trial simulations, selecting optimal timing of pharmacokinetic and pharmacodynamic assessments and estimating sample sizes.
  • Develop population pharmacokinetic models, evaluate drug-drug interactions and perform exposure-response analyses on data from phase II clinical trials of novel anti-tuberculosis regimens.
  • Perform predictions of site-of-disease drug exposures by integrating pre-clinical and clinical data in nonlinear mixed-effects models.

How to Apply?

Application Method: Online Application
Ref. No.: -

Application Procedure

Applicants should send a letter of intent expressing their motivation and experience in the field and overall related qualifications, with a curriculum vitae with names and addresses of professional references.

About the Department/Section/Group

The research team within the department of Pharmacy encompasses 3 professors, 1 associate professor, 6 researchers, and many PhD candidates and hospital pharmacy trainees. The position will be embedded in the Radboud Applied Pharmacometrics group and research group Pharmacology of anti-tuberculosis drugs, led by professor Rob Aarnoutse.


This position is embedded in the large international UNITE4TB research consortium. It is financed by the EU and has partners in Europe, Africa, Asia and South America. Collaboratively, a series of drug studies are being set up to combat tuberculosis. Every year, tuberculosis affects 10 million people, of whom more than 1.5 million die. Radboudumc is the coordinating body for UNITE4TB.

About the Employer:

Note or Other details

Working at Radboud university medical center means that you are ahead of the curve and working together on the healthcare of the future. And there is more. Our secondary terms of employment are impressive. These are fully tailored to you thanks to our Employment Conditions Selection Model. At Radboud university medical center, you will be given trust, and you will take the responsibility to handle everything together. We provide annual courses, both professional and personal.

  • In addition to your monthly salary and an annual vacation allowance of 8%, you will receive an end-of-year bonus of 8.3%.
  • If you work irregular hours, you will receive an allowance.
  • As a full-time employee (36 hours per week), you are entitled to approximately 168 vacation hours (over 23 days) per year.
  • Radboud university medical center pays 70% of the pension premium. You pay the rest of the premium with your gross salary.
  • You get a discount on health insurance as well: you can take advantage of two group health insurance plans. UMC Zorgverzekering and CZ collectief.

In addition to our terms of employment, we also offer employees various other attractive facilities, such as childcare and sports facilities. Want to learn more? Take a look at the Cao UMC.

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Contact details

All additional information about the vacancy can be obtained from Elin Svensson, researcher PharmacyUse the Apply button to submit your application.

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