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Medical Science, Postdoc Job – Gene editing and cell-based therapy, Oslo, Norway

University of Oslo, UiO

Norway

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Nov 1, 2021 23:59 (GMT +1)

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Institute of Clinical Medicine, Division of Cancer Medicine seeks Postdoctoral Fellow – gene editing and cell-based therapy at the University of Oslo, Norway – Nov 2021

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General Info

Position: Postdoc
No. of Positions: 1
Research Field:
Deadline to Apply: November 1, 2021(GMT +1)
Joining Date: -
Contract Period: 3 Years
Salary: NOK 534 400 - NOK 594 300 per annum

Workplace:
Institute of Clinical Medicine,
Division of Cancer Medicine
University of Oslo, UiO
Oslo,

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Qualification Details

  • PhD in relevant topic
  • Ability to independently design, plan, and execute experiments
  • Formal accreditation (FELISA C or similar) and experience working with mice models (requirement)
  • Experience in molecular biology techniques such as cell culturing, cloning, qPCR, ELISA, Western blotting, Immunohistochemistry (requirement)
  • Experience with CRISPR gene editing, stem cell work, and in vivo transplants is an advantage
  • Proficient in English language, both written and oral

The appointment requires a PhD or a degree equivalent to a Norwegian PhD in natural or medical sciences. A prerequisite for applicants who have not yet defended their thesis is that the thesis is submitted for assessment before the closing date for applications. Appointment to the position is dependent on the public defense of the doctoral thesis being approved.

Personal skills

  • Excellent communication and team working skills
  • Organized and structured
  • Flexible
  • Willing to learn new methods and techniques

Responsibilities/Job Description

According to the lab interest

How to Apply?

Online Application through "Apply Now" Button from this page or from advertisement webpage (URL below)

Reference Number: -
(If any, use it in the necessary place)

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Documents Required

The application must include:

  • Cover letter (statement of motivation, summarizing scientific work and research interest).
  • CV (summarizing education, positions, pedagogical experience, administrative experience and other qualifying activities).
  • Copies of educational certificates (academic transcripts only).
  • A complete list of publications.
  • Any research publications that the applicant wishes to be considered.
  • List of reference persons: 2-3 references (name, relation to candidate, e-mail and phone number).

The application with attachments must be delivered in our electronic recruiting system. Foreign applicants are advised to attach an explanation of their University's grading system. Please note that all documents should be in English (or a Scandinavian language).

In assessing the applications, special emphasis will be placed on the documented, academic qualifications, as well as the candidate’s motivation and personal suitability. Interviews with the best qualified candidates will be arranged.

It is expected that the successful candidate will be able to complete the project in the course of the period of employment.

About the Position

In the project, you will work on a bleeding disorder called inherited factor (F) VII deficiency. FVII is a vital protein in the blood coagulation process and an inherited deficiency of this protein is caused by mutations in the F7 gene leading to severely reduced activity of the FVII protein in the blood. Clinically, these patients experience frequent and sometimes severe bleeding episodes, and the only treatment today is replacement therapy that is expensive and invasive. We are using CRISPR gene editing and advanced cell reprogramming techniques to correct the mutation in the patients’ own cells and establishing transplant procedures in mice models to restore FVII activity and function. These important pre-clinical studies will lay the foundation for cell-based therapies in patient with FVII deficiency.

You will work closely with an experienced researcher on the project and together you will co-supervise a PhD student. The position is over a three-years period.

The main purpose of the fellowship is to qualify researchers for work in higher academic positions within their disciplines.

About the Employer: University of Oslo, UiO

Note or Other details

Please see the guidelines and regulations for appointments to Postdoctoral fellowships at the University of Oslo.

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Contact details

Project leader, professor Per Morten Sandset email: p.m.sandset@medisin.uio.no

Researcher, Maria Eugenia Chollet Dugarte email: m.e.c.dugarte@ous-research.no

Questions regarding the online application form can be addressed to Senior HR Adviser Thoril Kristiansen email: thoril.kristiansen@medisin.uio.no

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