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Erasmus MC, Netherlands – PhD Studies in Re-emergence of human noroviruses – Biology

Erasmus MC

The Netherlands

PhD position on Mechanism behind the (re-) emergence of human noroviruses is available at the Department of Viroscience, Erasmus MC, The Netherlands – Oct 2021.

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General Info

Position: PhD
No. of Positions: 1
Research Field: , , , ,
Deadline to Apply: Expired
Joining Date: -
Contract Period: 4 Years
Salary: According to Standard Norms

Workplace:
-
Department of Viroscience
Erasmus MC
Rotterdam,

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Qualification Details

  • We are looking for PhD students that are enthusiastic and highly motivated with a MSc degree or equivalent from an accredited academic program in Biology, Biomedical or Molecular Sciences, Immunology, or (Veterinary) Medicine.
  • Demonstrable experience with cell culture and various molecular and/or and virological techniques are necessary.
  • You have an excellent command of the English language, both oral and written. To be appointed, you must be able to obtain a certificate of good conduct.

Before you apply please check our conditions for employment.

Responsibilities/Job Description

Norovirus infections are a major cause of gastroenteritis in the general population worldwide. Novel norovirus variants frequently (re-) emerge in the human population and while some become the globally dominant other are only rarely detected. Erasmus MC manages Global NoroNet, the European norovirus surveillance network through which molecular and epidemiological data is collected from norovirus outbreaks to identify the predominant strains and newly emerged strains.

Your work will focus on identifying determinants of norovirus (re-) emergence and better understanding of why some norovirus genotypes are more prevalent than others. For this purpose, you will contribute to the NoroNet network by submitting and analysis of norovirus sequence data and communication with its members. Whole genome norovirus sequence data is acquired using NGS. This data will be used in combination with molecular methods and the norovirus culture system for genotype-to-phenotype mapping. Specifically, mutations affecting norovirus replication and antigenic properties will be investigated. This is a multidisciplinary project and potential candidates are required to have affinity for both wet-lab work and bioinformatics. This research will increase our knowledge on the mechanisms of norovirus emergence and will help to identify risks and design prevention and intervention strategies. The PhD project is funded through the VEO (Versatile emerging infectious disease observatory) that aims to provide evidence-based early warning, risk assessment and monitoring of emerging infectious diseases (EIDs) and antimicrobial resistance.

Candidates are expected to obtain their PhD in 4 years, with Prof. Dr. M.P.G. Koopmans, Head of the Department as promotor.

How to Apply?

Online Application through "Apply Now" Button from this page or from advertisement webpage (URL below)

Reference Number: -37.18.21.TD
(If any, use it in the necessary place)

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Documents Required

Documents required to complete the online application process

About the Department

The Department of Viroscience at Erasmus MC employs more than 110 employees of different disciplines and runs an extensive experimental research program on the epidemiology, pathogenesis, prevention and treatment of infections by human and animal viruses. All necessary equipment to carry out the research proposed in the projects is available within the setting of the department. The Department of Viroscience harbors well-equipped clinical and experimental virology labs, in which all the virology, molecular biology, pathology and immunology techniques necessary for these projects are operational.

About the Employer: Erasmus MC

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Contact details

For more information about this position, please contact Miranda de Graaf, Supervisor, phone number: (+31)(0)10 704 40 04 or e-mail: m.degraaf@erasmusmc.nl.  For queries regarding your application, please contact Jerry Chandansingh, Recruiter, by phone number: +31 (0)6 500 310 06.

Advertisement Details: PhD candidate on the project "Mechanism behind the (re-) emergence of human noroviruses"

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