Doctoral student in Intensified production process of AAV for gene therapy with Biotechnology as Third-cycle subject where focus of the project is adeno-associated virus bioproduction in bioreactor for gene therapy with master’s degree is available at School of Engineering Sciences in Chemistry, Biotechnology and Health at KTH Royal Institute of Technology, Sweden April-2022

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General Info

Position: Doctoral Student
No. of Positions: 1
Research Field: , ,
Deadline to Apply: Expired
Joining Date: ASAP
Contract Period: 4 years
Salary: According to standard norms

Workplace:
Biotechnology

KTH Royal Institute of Technology, Sweden

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Qualification Details

To be admitted to postgraduate education (Chapter 7, 39 § Swedish Higher Education Ordinance), the applicant must have basic eligibility in accordance with either of the following:

  • passed a second cycle degree (for example a master's degree),
  • completed course requirements of at least 240 higher education credits, of which at least 60 second-cycle higher education credits, or
  • acquired, in some other way within or outside the country, substantially equivalent knowledge
  • The applicant should have a master in biotechnology, bioprocess technology, engineering biology, chemical/biochemical engineering. Knowledge and experience of mammalian cell culture bioprocess and/or production of viral vectors are advantageous.

In addition to the above, there is also a mandatory requirement for English equivalent to English B/6, read more here

Responsibilities/Job Description

Third-cycle subjectBiotechnology

The focus of the project is adeno-associated virus bioproduction in bioreactor for gene therapy. The purpose is the development of an intensified process using an established human cell line for the production of these viral vectors, where in particular high cell concentration is obtained by perfusion operation. The project will be part of the research ‘milieu’ GeneNova funded by Vinnova, and which is driven in collaboration with the companies AstraZeneca, Vironova, AlfaLaval, Combigene, Biotage, Ziccum, as well as academic groups of KTH, Karolinska Institutet and Uppsala University.

Supervision: The doctoral student will be supervised by: Associate Professor Veronique Chotteau. Decisions are made on admission

Selection

In order to succeed as a doctoral student at KTH you need to be goal oriented and persevering in your work. During the selection process, candidates will be assessed upon their ability to:

  • independently pursue his or her work
  • collaborate with others,
  • have a professional approach and
  • analyse and work with complex issues.
  • flexibility
  • good written and oral communication skills

After the qualification requirements, great emphasis will be placed on personal competency.

How to Apply?

Application Method: Online Application
Ref. No.: C-2022-0459

Application Procedure

Apply for the position and admission through KTH's recruitment system. It is the applicant’s responsibility to ensure that the application is complete in accordance with the instructions in the advertisement.

Applications must be received at the last closing date at midnight, CET/CEST (Central European Time/entral European Summer Time).

Applications must include the following elements:

  • CV including your relevant professional experience and knowledge.
  • Application letter with a brief description of why you want to pursue research studies, about what your academic interests are and how they relate to your previous studies and future goals. (Maximum 2 pages long)
  • Copies of diplomas and grades from previous university studies and certificates of fulfilled language requirements (see above). Translations into English or Swedish if the original document is not issued in one of these languages.Copies of originals must be certified.
  • Representative publications or technical reports. For longer documents, please provide a summary (abstract) and a web link to the full text.
  • Two references.

About the Doctoral degree

Information regarding admission and employment

Only those admitted to postgraduate education may be employed as a doctoral student. The total length of employment may not be longer than what corresponds to full-time doctoral education in four years ' time. An employed doctoral student can, to a limited extent (maximum 20%), perform certain tasks within their role, e.g. training and administration. A new position as a doctoral student is for a maximum of one year, and then the employment may be renewed for a maximum of two years at a time.

 

About the Employer:

Offer

  • Veronique Chotteau’s group is the Cell Technology group (CETEG) at Dept. Industrial Biotechnology. Chotteau has a long experience of developing biopharmaceutical drug bioprocesses for human therapy. Chotteau is leader in perfusion bioprocessing operated at very high cell concentration. CETEG's activities focus on the production of biological drugs, proteins and viral vectors. Chotteau is the Director of the Competence Centre AdBIOPRO for Advanced Bioproduction by Continuous Processing, Coordinator of the European project iConsensus within the Innovative Medicines Initiative (IMI2), partner of the Competence Centre for Advanced Medical Product CAMP, partner of the Marie-Curie EU project STACCATO, and partner of the research milieu GeneNova.

Other information

Striving towards gender equality, diversity and equal conditions is both a question of quality for KTH and a given part of our values.

For information about processing of personal data in the recruitment process please read here.

We firmly decline all contact with staffing and recruitment agencies and job ad salespersons.

Disclaimer: In case of discrepancy between the Swedish original and the English translation of the job announcement, the Swedish version takes precedence.

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Contact details

Veronique Chotteau, +46 8 790 96 28

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