PhD Position in Karolinska Institutet Sweden

Doctoral (PhD) student position in Preclinical nuclear medicine – Karolinska, Sweden, 2022

Sweden

Doctoral (PhD) student position in preclinical nuclear medicine to develop cutting-edge imaging and therapy platform technologies for patients with cancer or cardiovascular diseases, at Karolinska Institutet, Sweden 2022

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General Info

Position: PhD
No. of Positions: 1
Research Field:
Deadline to Apply: Expired
Joining Date: ASAP
Contract Period: 4 Years
Salary: According to standard norms

Workplace:
MedTechLabs

Karolinska Institute (KI), Sweden

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Qualification Details

In order to participate in the selection for a doctoral position, you must meet the following general (A) and specific (B) eligibility requirements at latest by the application deadline.

It is your responsibility to certify eligibility by following the instructions on the web page Entry requirements (eligibility) for doctoral education.

A) General eligibility requirement

You meet the general eligibility requirement for doctoral/third-cycle/PhD education if you:

  1. have been awarded a second-cycle/advanced/master qualification (i.e. master degree), or
  2. have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level, or
  3. have acquired substantially equivalent knowledge in some other way in Sweden or abroad.*

Follow the instructions on the web page Entry requirements (eligibility) for doctoral education.

*If you claim equivalent knowledge, follow the instructions on the web page Assessing equivalent knowledge for general eligibility for doctoral education.

B) Specific eligibility requirement

You meet the specific eligibility requirement for doctoral/third-cycle/PhD education if you:

- Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school.

Follow the instructions on the web page English language requirements for doctoral education.

Verification of your documents Karolinska Institutet checks the authenticity of your documents. Karolinska Institutet reserves the right to revoke admission if supporting documents are discovered to be fraudulent. Submission of false documents is a violation of Swedish law and is considered grounds for legal action.

(A) and (B) can only be certified by the documentation requirement for doctoral education.

Skills and personal qualities

We are looking for a doctoral candidate with a background in (bio)medical sciences, (bio)chemistry, (radio)pharmacy or equivalent and demonstrated laboratory skills. Some prior knowledge about tumour biology is required. Experience with radiochemistry and/or molecular imaging is considered an advantage. The project will include small animal handling, so prior experience in this field is appreciated. The candidate should be a strong team player with excellent collaborative skills. Good communication skills in English are required.

Responsibilities/Job Description

The student will develop a novel radioligand therapy for patients with brain cancer. First, tumour-targeting small molecules, peptides or antibodies will be labelled with radionuclides for molecular imaging (e.g. PET, SPECT). These will be extensively validated in in vitro and in vivo tumour models. Next, the most promising radioligands will be translated into their therapeutic counterparts, which will then be evaluated in in vivo therapy studies.

Applications are invited from highly motivated, ambitious students with a positive, can-do attitude. At the end of your doctorate project, you will:

  • have a broad understanding of the molecular biology and pathophysiology of brain cancer, as well as preclinical cancer models;
  • have in-depth knowledge of (radio)chemical methodology development;
  • have profound knowledge on molecular imaging, pharmacokinetics and radioligand therapy;
  • have developed a critical, independent, creative way of hypothesis-driven scientific thinking;
  • know how to independently and timely conduct experiments and accurately analyse experimental data;
  • know how to present research data through peer-reviewed manuscripts, a high-quality thesis and presentations at (inter)national conferences;
  • have high ethical research standards and be able to critically assess the impact of your research on society and the environment.

How to Apply?

Application Method: Online Application
Ref. No.: STÖD 2-1029/2022

Application Procedure

Submit your application and supporting documents through the Varbi recruitment system. Use the button in the top right corner and follow the instructions. We prefer that your application is written in English, but you can also apply in Swedish.

Your application must contain the following documents:

- A personal letter and a curriculum vitae

- Degree projects and previous publications, if any

- Any other documentation showing the desirable skills and personal qualities described above

- Documents certifying your general eligibility (see A above)

- Documents certifying your specific eligibility (see B above)

Selection

A selection will be made among eligible applicants on the basis of the ability to benefit from doctoral education. The qualifications of the applicants will be evaluated on an overall basis.

Karolinska Institutet uses the following bases of assessment:

- Documented subject knowledge of relevance to the area of research

- Analytical skill

- Other documented knowledge or experience that may be relevant to doctoral studies in the subject.

About the Department/Section/Group

In our group, we aim to develop cutting-edge imaging and therapy platform technologies for patients with cancer or cardiovascular diseases. In this project, our primary focus lies with the development of novel molecular imaging and radionuclide therapy strategies for patients with brain cancer. We are offering a unique opportunity to conduct high-quality (pre)clinical research at a world-renowned institute, where you will exploit your scientific creativity, learn new skills, collaborate with national and international leaders in the field and, ultimately, contribute to the improved healthcare of patients with cancer. Our research is highly multidisciplinary, combining recent developments from radiology, oncology, chemistry and molecular biology into innovative nuclear medicine designs, and is carried out at the state-of-the-art research facilities of the Karolinska Institutet and MedTechLabs .

About the Employer:

Note or Other details

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. As a doctoral student you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. You will be employed on a doctoral studentship which means that you receive a contractual salary. Employees also have access to our modern gym for free and receive reimbursements for medical care.

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Contact details

  • Vendela Breeze, HR administrator, +46 8-524 832 82
  • Jeroen Goos, Assistant professor, [email protected]

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