University of Copenhagen (UCPH) invites applications for a postdoc position at the Department of Plant and Environmental Sciences, Section of Plant Glycobiology Faculty of Science, Denmark – Jan 2023
A PhD degree in Structural Biology, Biochemistry, Biophysics, Nanotechnology or similar.Excellent English communication skills and good interpersonal skills. Practical experience with one or more of:
- Cryo-Electron Microscopy and/or tomography (cryo-EM/ET)
- Structural Biology techniques (e.g. X-ray crystallography)
- Biophysics & Advanced microscopy
- Plant protoplast isolation
- Professional qualifications relevant for the position.
- Relevant work experiences.
- Language skills.
- Creative thinking
The postdoc position will be associated with the Plant Cellulose Synthesis research group and carried out with Assist. Prof. Kristian E. H. Frandsen and Prof. Staffan Persson. The work aims to structural visualise the large Cellulose Synthase protein complex (CSC) in planta responsible for plant cell wall formation. The research will range from culturing single plant cells and visualizing large protein complexes in vivo using advanced light microscopy (confocal fluorescence) to determining the organization and molecular structures of protein complexes in their near native environment in vivo using state-of-the-art cryo-electron tomography (cryo-ET) and subtomogram averaging (STA). The postdoc position covers structural cell biology and will be based in the Plant Cellulose Synthesis research group in a highly cross-disciplinary team that includes the full range of computational structural biology, microscopy, molecular biology and biochemistry (> 20 people). This postdoc will prepare single cell cultures (protoplasts) derived from plant tissue of transgenic marker lines (A. thaliana and/or Nicotiana tabacum BY-2) and localize the CSC complex in vivo using correlative light and electron microscopy (CLEM) through the group’s access to microscope facilities e.g. Center for Advanced Bioimaging (CAB) and Core Facility for Integrated Microscopy (CFIM) both located at the University of Copenhagen. A substantial part of the postdoc will be carried out at Biozentrum, University of Basel in the group of Prof. Benjamin Engel, which are international experts in preparing suitable cryo-frozen samples for cryo-electron microscopy/tomography (EM/ET) including novel focused ion beam (FIB) milling lift-out approaches. The ideal candidate will be part of an exciting international team striving to understand the structural details of enzyme complexes responsible for plant cell morphology. The candidate is expected to have a solid foundation in structural cell biology and optimally hands-on experience with cryo-electron microscopy and/or tomography (cryo-EM/ET) with a supporting strong publication record. Expertise in Structural Biology techniques e.g. X-ray crystallography is considered a plus. You will also be expected to engage in teaching, supervision of students and lab technicians, as well as actively apply for funding.
How to Apply?Application Method: online_applicationRef. No. -
The application, in English, must be submitted electronically by clicking APPLY NOW below. Please include
- Curriculum vitae
- Diplomas (Master and PhD degree or equivalent)
- Research plan – description of current and future research plans
- Complete publication list
- Separate reprints of 3 particularly relevant papers
Note or Other detailsTerms of employment The position is covered by the Memorandum on Job Structure for Academic Staff. Terms of appointment and payment accord to the agreement between the Ministry of Taxation and The Danish Confederation of Professional Associations on Academics in the State. Negotiation for salary supplement is possible.
Inquiries about the position can be made to Kristian E. H. Frandsen email: firstname.lastname@example.org and Staffan Persson email: email@example.com.