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Bioinformatics, PhD studies – Evolution of vertebrate non-coding sequences and genome size

Nord University

Norway

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Nov 1, 2021 23:59 (GMT +1)

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PhD fellowship – evolution of vertebrate non-coding sequences and genome size project is available at the Faculty of Biosciences and Aquaculture, Nord University- Norway, Nov 2021

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General Info

Position: PhD
No. of Positions: 1
Research Field: , , , , ,
Deadline to Apply: November 1, 2021(GMT +1)
Joining Date: -
Contract Period: Not Mentioned
Salary: NOK 491.200 per year

Workplace:
-
Faculty of Biosciences and Aquaculture (FBA)
Nord University
Bodo,

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Qualification Details

MSc or equivalent in bioinformatics, computational biology, computer science, physics, mathematics, biology (given computational experience) or similar.

Grade average of B or better (or equivalent score) both for the programme in total and the master’s thesis.

The candidate must have some programming experience and will ideally have a strong background in statistics. Students of computational biology, computer science, physics, mathematics and biology (given computational experience) are encouraged to apply.

Proficiency in oral and written English is essential and knowledge of a Scandinavian language is beneficial for the position.

The successful candidate will join the PhD program in Aquatic Biosciences at Nord University and is expected to complete the study within the three-year project period.

The candidate should fulfill the admission requirements and participate in the training component stipulated in regulations of the PhD program. Application for admission to the program must be submitted within three months after taking up the position. For admission requirements and regulations, see our web page.

Responsibilities/Job Description

According to the lab interest

How to Apply?

Online Application through "Apply Now" Button from this page or from advertisement webpage (URL below)

Reference Number: -30072101
(If any, use it in the necessary place)

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Documents Required

Applicants for this position are required to provide the following:

  • Motivation letter outlining the candidate’s suitability for this position and relevant experience (maximum 1 page)
  • A research outline specifying how the candidate proposes to implement the project (maximum 1 page)
  • Curriculum vitae, including a list of publications (maximum 3 pages)
  • Certified copies of academic degree transcripts and any other relevant qualifications
  • Contact details for at least two referees
  • Signed consent form PhD (if relevant)

All documents must be uploaded as attachments to the electronic application form.

It is the applicant's responsibility to submit the complete documentation within the deadline.

After the application period has expired a list of applicants will be published. Note that, in special cases, the identity of particular applicants to a position may be made public even when that applicant has requested that their application be processed confidentially. Applicants requesting an exemption from publication of their identity must explain their reasons for doing so in their application. In this case, advance notice will be given in the event of a decision to make any information about the applicant public.

Refnr. 30072101

About the Position

We are offering a PhD position to study the evolution of vertebrate non-coding sequences and genome size. Although the vertebrate protein coding gene repertoire is relatively stable, genome size varies by several orders of magnitude from 0.3 to around 50 gigabases (e.g. pufferfish vs. lungfishes). The roles played by this variable non-coding DNA remains hotly debated, with options ranging from ‘mostly junk’, to ‘almost all functional’. Similarly, what evolutionary pressure have contributed to the genome size variance remain unknown.

Recent advances in high-throughput sequencing technologies have resulted in the availability of large numbers of well assembled genomes as well as sequence variance data from a growing number of wild species subject to natural selection. This makes it possible to not only infer how genome size has changed, but also to investigate the likely evolutionary processes underlying these changes through the use of population genetics methodologies.

This project will make use of around 200 whole genome sequences and phylogenetic and population genetic approaches to determine how and why non-coding sequences evolve. The research includes both methods development and analyses of sequence changes in non-coding sequence. The research will make use of the highly variable teleost genome sizes in order to identify the evolutionary pressures and mechanisms underlying genome size evolution.

The proposed research is pure bioinformatics, and the student will need to gain an understanding of sequence alignment and phylogenetic tree building approaches and be able to efficiently implement at least some of these. In order for this the student should be or become proficient in R, C (or C++), SQL, Bash and a general-purpose scripting programming language like Perl or Python.

About the Employer: Nord University

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Contact details

Further information about the position can be obtained by contacting :

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