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Bioinformatician Job – Translational Tumor Genetics, Radboudumc, Netherlands 2022

Radboud university medical center, The Netherlands

Radboudumc invites applications for a bioinformatician with a focus on tumor genetics, will participate in setting up innovative bioinformatic analyses methods and workflows for somatic genetic analyses, at the Departments of Human Genetics and Pathology, The Laboratory tumor genetics (LTG), The Netherlands -Jan 2022

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General Info

Position: Bioinformatician
No. of Positions: 1
Research Field: ,
Joining Date: ASAP
Contract Period: 4 Years
Salary: According to Standard Norms

Departments of Human Genetics and Pathology
Radboud university medical center
Radboud university medical center, the Netherlands
Nijmegen, The Netherlands

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Qualification Details

You have the drive to optimize patient care through development and implementation of innovative bioinformatic solutions in close collaboration with laboratory specialists and other members of the bioinformatic team.


  • A Master degree in bioinformatics or equivalent.
  • Experience in bioinformatic genetic analyses.
  • Preferably experience in the field of somatic tumor genetics.
  • A PhD in bioinformatics or related discipline is preferred.
  • Effective communication skills, which includes an ability to engage in technical conversations across disciplines, notably including medical disciplines.
  • The mentality of a team player who inspires and gets inspired.

Responsibilities/Job Description

The bioinformatician will closely collaborate with two bioinformaticians who are dedicated to the development and implementation of novel analyses for tumor diagnostic applications to identify acquired aberrations and will be embedded in the bioinformatics team of the department of Human Genetics that mainly focuses on constitutional genetic aberrations.

LTG is a collaborative effort between the departments of Pathology and Human Genetics, that offers the latest genetic technologies for the diagnosis and treatment selection of cancer patients and performs internationally recognized research on tumor genetics.

LTG works closely with the diagnostics division of the department of Human Genetics for the use of innovative genetics technology such as short and long-read sequencing technology. LTG and the diagnostics division are internationally recognized for applying the latest genetic technologies in patient diagnostics and for their expertise in cancer molecular diagnostics, sequencing technologies and bioinformatics.

Tasks and responsibilities

  • Implementing and developing innovative technologies and bioinformatics for tumor diagnostics in close collaboration with laboratory specialists.
  • Implementation of innovative tumor diagnostics tools and workflows.

How to Apply?

Online Application through "Apply Now" Button from this page

Reference Number: -
(If any, use it in the necessary place)

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Documents Required

We would like to receive your application before 27 January 2022. We will then contact you shortly.

What else can you expect?

When you begin employment, we will request a certificate of conduct (VOG) and, depending on the position, you may be screened. You do not need to do anything for this; we will inform you later.  Radboud university medical center is an employer that welcomes everyone. Every colleague brings valuable experience, expertise, and creativity. We believe in the benefits of a diverse and inclusive organization. #weareradboudumc

Read more about our application procedure or take a look at the frequently asked questions.  We are recruiting for this vacancy ourselves. We only accept applications directly from the applicants themselves, but intermediaries are welcome to share our vacancies in their networks.​

About the Department

Radboudumc departments of Human Genetics and Pathology closely collaborate in the laboratory of tumor genetics (LTG), that consists of 9 laboratory  specialists, 40 technicians and has a close collaboration with the PI groups of Richarda de Voer and Marjolijn Ligtenberg with currently 10 PhD students. LTG provides clinical molecular diagnostics, both somatic and germline, for diagnostic and predictive purposes.

The department of Human Genetics consists of a diagnostics, research and clinical division. Within the diagnostics division (135 FTE) the bioinformatics group (15 FTE) is responsible for developing and maintaining bioinformatics workflows for the analysis of exome, genome and long-read sequencing data. Within this group, currently two bioinformaticians are dedicated to the development and implementation of novel analyses for tumor diagnostic applications. This includes the analysis of TSO500, WES on tumor tissue, and of WGS and targeted panels for liquid biopsies.

The bioinformatics group offers access to a complete development setup, based on the Atlassian stack and Java. In addition, there is a large knowledge base on exome and genome analysis, statistics methodology, R, Python, Java, machine learning and other bioinformatic related topics. The development of novel analyses methods is conducted on a high-performance compute environment (>600 cores, 2.5Pb storage) that supports large-scale genome analyses and the setup of diagnostic workflows.

The LTG and the bioinformatics group collaborate with the Radboud Genome Technology Center Genomics for applying novel sequencing technologies in tumor diagnostics. CGAL hosts the latest genome technologies such as exome and genome, TSO500 and Molecular inversion probe (MIPs) technology through Illumina NextSeq 500 or NovaSeq, and long-read sequencing through PacBio Sequel IIe instruments. In addition, the laboratory hosts a Bionano Saphyr instrument for the detection of complex structural genome variation.

About the Employer: Radboud university medical center, the Netherlands

Terms of Employment

Working at Radboud university medical center means that you are ahead of the curve and working together on the healthcare of the future. And there is more. Our secondary terms of employment are impressive. These are fully tailored to you thanks to our Employment Conditions Selection Model. At Radboud university medical center, you will be given trust, and you will take the responsibility to handle everything together. We provide annual courses, both professional and personal.

  • In addition to your monthly salary and an annual vacation allowance of 8%, you will receive an end-of-year bonus of 8.3%.
  • If you work irregular hours, you will receive an allowance.
  • As a full-time employee (36 hours per week), you are entitled to approximately 168 vacation hours (over 23 days) per year.
  • Radboud university medical center pays 70% of the pension premium. You pay the rest of the premium with your gross salary.
  • You get a discount on health insurance as well: you can take advantage of two group health insurance plans. UMC Zorgverzekering and CZ collectief.

In addition to our terms of employment, we also offer employees various other attractive facilities, such as childcare and sports facilities. Want to learn more? Take a look at the CAO UMC.

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Contact details

All additional information about the vacancy can be obtained from Prof.dr. Marjolijn Ligtenberg, Head of the Laboratory Tumor Genetics via  +31 (24) 361 77 49 of from Dr. Christian Gilissen, Head of the bioinformatics unit of the Department of Human Genetics via +31 (24) 366 89 40. Use the Apply button to submit your application.

Advertisement Details: Bioinformatician translational tumor genetics

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