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Assistant Professorship at Cellular Medicine, Molecular Medicine – UCPH, Denmark – Nov 2021

Denmark, University of Copenhagen (UCPH)

We are looking for one highly motivated and skilled researcher with experience in virus biology, gene targeting, mucin type O-GalNAc-biology, and O-glycoproteomics, at the Department of Cellular and Molecular Medicine at the Faculty of Health and Medical Sciences, University of Copenhagen, Denmark

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General Info

Position: Assistant Professorship
No. of Positions: 1
Research Field: , ,
Deadline to Apply: Expired
Joining Date: Feb 1, 2022
Contract Period: 2 Years
Salary: 31,065 DKK/Month

Workplace:
Department of Cellular and Molecular Medicine (ICMM)
Copenhagen Center for Glycomics
University of Copenhagen (UCPH)

Copenhagen, ,

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Qualification Details

  • You have a PhD in Biochemistry / Glycobiology.
  • You possess significant research experience and publication records in the virology, mass spectrometry, and glycobiology field with emphasis on the topics mentioned above.
  • Proficient communication skills and ability to work in teams.
  • Excellent English skills written and spoken.

Assessment of applicants will primarily consider their level of documented, internationally competitive research. The ability to attract external funding will be considered together with outreach qualifications. Teaching qualifications are not mandatory but documented teaching qualifications and teaching experience will be considered.

Responsibilities/Job Description

CCG houses a high throughput CRISPR/Cas9 gene targeting platform and has developed a comprehensive, validated CRISPR library (GlycoCRISPR) to dissect the human glycome. We have used this to create a large library of isogenic human cells with different glycosylation capacities, which constitutes a cell-based glycan array (GlycoDisplay). This resource enables the display and dissection of interactions with glycans and the production of glycoproteins with custom-designed glycans.

We have over the last years mapped the O-glycoproteome of several human enveloped viruses using mass spectrometry and found that O-glycans are important for viral propagation, epithelial infectivity, and immune recognition. Using the glycoengineered cells, we will dissect the importance of individual glycans for the propagation of enveloped viruses. In addition, we will search for how the individual glycans interfere with the attachment, propagation, release, and spread of herpes virus, and investigate the importance of site-specific glycosylation. We expect that the results will help us understand the molecular mechanism, including receptors and signalling proteins, by which glycosylated structures on viruses help in the propagation of enveloped viruses and how they influence the innate and adaptive immune system.

The successful candidate will be responsible for the development and expansion of the GlycoVirology research program supporting the research activities at CCG. The candidate will be expected to lead a group that develops tools and methodologies enabling interrogation and understanding of the glycome in the context of enveloped viruses.

The position is aimed towards an individual who is able to take leadership within his/her topic of interest, and is expected to develop collaborative and interdisciplinary networks, including primarily responsibilities of:

  • research, including publication/academic dissemination duties.
  • research-based teaching.
  • sharing knowledge with society.
  • participation in formal pedagogical training program for assistant/associate professors.

How to Apply?

Online Applicationhttps://candidate.hr-manager.net/ApplicationInit.aspx?cid=1307&ProjectId=155264&DepartmentId=19000&MediaId=4636&SkipAdvertisement=true through "Apply Now" Button from this page

Reference Number: -
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Documents Required

Furthermore, your application must include the following documents/attachments – all in PDF format:

  1. Motivated letter of application (max. one page).
  2. CV incl. education, work/research experience, language skills and other skills relevant for the position.
  3. A certified/signed copy of a) PhD certificate and b) Master of Science certificate.
  4. List of publications.
  5. Teaching portfolio (if applicable).

About the Project/Department

Copenhagen Center for Glycomics (CCG) is a Danish National Research Center devoted to the study of diseases caused by defects in the biosynthesis and structure of complex carbohydrates. Currently, CCG comprises 5 research groups and hosts about 10 post docs and 15 PhD students in addition to Master students and guest researchers. CCG strives be a leader in glycosciences in pioneering transformation of the field towards wider integration into mainstream cell biology by developing experimental strategies, informatics approaches, and sustainable resources amenable not only to experts. These initiatives include GlycoCRISPR, GlycoDisplay (GAGOme), GlycoDesign, and GlycoInteract.

We aim to facilitate discovery of diseases caused by altered glycosylation, develop new diagnostic and therapeutic tools, and identify new ways to design and produce improved glycoprotein drugs. CCG is a cutting-edge interdisciplinary research and training Center located on the 10th floor of the new Mærsk Tower science building within the Department of Cellular and Molecular Medicine (ICMM). CCG has state-of-the-art facilities for mass spectrometry, flow cytometry, cell engineering, and glycan arrays, and the senior leaders hold diverse expertise in all areas of glycosciences. Our core valuables include glycoproteome data and bioinformatics tools, validated gene editing tools, glycoengineered cell libraries, and design matrices for recombinant production of glycotherapeutics. CCG hosts an international seminar series, PhD courses in glycobiology and gene editing, and participates in ICMMs education program.

More information can be found at www.glycomics.ku.dk.

About the Employer:

Note or Other details

The employment as assistant professor is a full-time (37 working hours per week in average) and fixed-term position for 2 years. Starting date is 15 February 2022 or after agreement.

Salary, pension, and terms of employment will be in accordance with the agreement between the Ministry of Finance and AC (Danish Confederation of Professional Associations). Currently, the monthly salary starts at DKK 31,065 / approx. EUR 4,169 (October 2021-level). Depending on qualifications, a supplement may be negotiated. The employer will pay an additional 17.1 % to your pension fund.

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Contact details

For further information please contact Mel Robbins by e mail: mrobbins@sund.ku.dk.

Foreign applicants may find this link useful: www.ism.ku.dk (International Staff Mobility).

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