DTU Health Tech is seeking a highly experienced and motivated formulation scientist to join our Distinguished Innovator project team. Our team is dedicated to local delivery of antibiotics and nucleotides, with a primary focus on treating infections and inflammation in soft tissue, bones, and joints such as osteomyelitis and osteoarthritis.

If you are a talented researcher in formulation and analytical chemistry with a passion for translational research, we invite you to apply for this exciting opportunity to work with us. As our new colleague, you will contribute to developing innovative treatments for these debilitating diseases, which is of utmost importance for patients and society at large, as it can prevent hospitalization and reduce healthcare costs.

The Distinguished Innovator project team is part of a larger group at DTU Health Tech, the Colloids & Biological Interfaces (CBIO). The CBIO group aims to improve and develop new treatments for a broad range of diseases. Our goal is to prevent disability and improve the quality of life of patients. The aim of the current project is further to combat the occurrence of antimicrobial resistance.As part of our expert team, you will collaborate on formulation strategies for delivering antibiotics and nucleotide technology to treat infection and manage inflammation in bone, soft tissue, and joints. The university is located in the greater Copenhagen area, which is renowned for its excellent standards of living and welfare system. Join us in our quest to improve healthcare through innovative research.

The job

We are developing innovative platform technologies to facilitate local delivery of antibiotics, peptides, and nucleotides for treating infections and regulating the inflammatory stage. Our technology has already shown strong proof of concept in translational models, and we are currently focused on optimizing it for use in joints and as a coating for orthopaedic hardware.

You will lead development of materials for local drug delivery, investigate interactions of these materials with orthopaedic hardware, conduct material stability studies and determine in vitro and in vivo drug release profiles. The team comprises experienced veterinarians, microbiologists, chemists and has a broad range of collaborators in Danish hospitals with expertise in e.g. orthopaedic surgery to guide the project.Your contributions will be critical to meeting project milestones, and you will have an immediate impact on the team from day one. This position provides a unique opportunity to work on an important healthcare project and access outstanding scientific platforms at DTU. The project is interdisciplinary, and teamwork, efficiency, and communication are essential.

Responsibilities

Formulation of antibiotics and oligonucleotides.
Develop depot formulations for sustained release of actives.
Conduct stability studies of lead formulations.
Perform bench testing of formulations, e.g. for coating purposes.
Develop analytical methods for PK/BD studies.
Documentation and communication of obtained results.

Our expectations of you

You must hold a PhD degree (or equivalent) ideally in pharmaceutical science or formulation, physical or analytical chemistry and have strong focus and interest in translation of technologies.

Qualifications:

Experience with formulation of small molecule drugs.
Experience with soft materials and methods for physical chemical characterization of these.
Solid experience with HPLC and ELISA, fluorescence spectroscopy.
Experience with PK/BD studies is an advantage.
Knowledge of oligonucleotide technology is an advantage.
Knowledge of local depot drug delivery technologies is an advantage.
Knowledge of infection and inflammation diseases is an advantage.

We offer

DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.

Salary and terms of employment

The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. The period of employment is 1 year. Expected starting date is 1 June 2023 – or according to mutual agreement.You can read more about career paths at DTU here.

Further information

Further information may be obtained from Associate Professor Jonas R. Henriksen, +45 4058 2866.

You can read more about DTU Health Tech at www.healthtech.dtu.dk/english.

If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark.

Application procedure

Your complete online application must be submitted no later than 7 April 2023 (Danish time). Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link “Apply online”, fill out the online application form, and attach all your materials in English in one PDF file.

The file must include:

Application (cover letter)
CV
Academic Diplomas (MSc/PhD – in English)
List of publications

Applications received after the deadline will not be considered.All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply.

DTU Health Tech

DTU Health Tech engages in research, education, and innovation base on technical and natural science for the healthcare sector. The Healthcare sector is a globally expanding market with demands for the most advanced technological solutions. DTU Health Tech creates the foundation for companies to develop new and innovative services and products which benefit people and create value for society. DTU Health Techs expertise spans from imaging and biosensor techniques, across digital health and biological modelling, to biopharma technologies. The department has a scientific staff of about 210 persons, 130 PhD students and a technical/administrative support staff of about 160 persons, of which a large majority contributes to our research infrastructure and related commercial activities.