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2 PhD Fellows in Hematology, Immunology, Cell biology, Molecular biology – UiT, Norway

Norway

2 PhD positions are available at the Department of Clinical Medicine, Faculty of Health Sciences with the research group Thrombosis Research Center (TREC). One of the positions is affiliated with the project “Hypoxia-regulated proteins and risk of venous thromboembolism”, the other with the project “Novel biomarkers of cancer associated thrombosis (NOR-CAT)”

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General Info

Position: PhD
No. of Positions: 2
Research Field: , ,
Deadline to Apply: Expired
Joining Date: ASAP
Contract Period: 4 Years
Salary: According to standard norms

Workplace:
Faculty of Health Sciences

UiT - University of Tromsø - The Arctic University of Norway

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Qualification Details

These positions requires a master’s degree or equivalent in biology or bioinformatics. Applicants must document fluency of in English and be able to work in an international environment. If you are near completion of your master’s degree, you may still apply.

Research experience in thrombosis and haemostasis or omics-based research, haematology, immunology, cellular and/or molecular biology will be considered an advantage.

The candidates must be able to work systematically, independently and have the ability to work in an interdisciplinary research team. Emphasis will be placed on the communicative and collaborative skills, as well as personal suitability and the motivation and specific interest in the project.

As many as possible should have the opportunity to undertake organized research training. If you already hold a PhD or have equivalent competence, we will not appoint you to this position.

Responsibilities/Job Description

Venous thromboembolism (VTE) is a complex disease, leading to short- and long-term complications, including death. The disease originates in the valvular sinuses of the deep veins in the limbs, in a milieu characterized by severe oxygen deprivation, i.e. hypoxia and vortex flow (stasis). These conditions are thought to activate and transform intravascular cells (endothelial cells, monocytes, neutrophils and platelets) to upregulate their proinflammatory and procoagulant activity and subsequent release of procoagulant extracellular vesicles (EVs). Although hypoxia can trigger the activation of intravascular cells, the exact chain of events, and which cellular and molecular processes that lead to the formation of venous thrombi, are still unclear. In this project the successful PhD candidate will study whether hypoxia-related proteins are associated with VTE risk. The cellular and molecular mechanisms by which such hypoxia-regulated proteins operate will be studied in cellular models of VTE.

The work will involve both clinical epidemiology and experimental wet lab work. Cancer is a strong and independent risk factor for VTE. Observational studies have shown that 20-25% of all first VTE events are cancer-related, whereas the cumulative incidence of VTE in cancer varies widely and reported to maximize to 12-15%. Present predictive biomarkers and risk assessment models of VTE risk in cancer has limited applicability in clinical practice for risk stratification and guidance on preventive anticoagulant treatment. The present project will use omics data (genomics and proteomics) derived from unique population-based cohorts to discover and validate predictive biomarkers of VTE in cancer patients and improve existing risk assessment models.

How to Apply?

Application Method: Online Application
Ref. No.: -

Application Procedure

  • Cover letter explaining your motivation and research interests
  • CV
  • Diploma for bachelor's and master's degree
  • Transcript of grades/academic record for bachelor's and master's degree
  • Explanation of the grading system for foreign education (Diploma Supplement if available)
  • Documentation of English proficiency
  • References with contact information
  • The works (published or unpublished) that the applicant wishes to be taken into consideration during the assessment process.

Qualification with a master’s degree is required before commencement in both positions. If you are near completion of your master’s degree, you may still apply and submit a draft version of the thesis and a statement from your supervisor or institution indicating when the degree will be obtained. You must still submit your transcripts for the master’s degree with your application.

All documentation to be considered must be in a Scandinavian language or English. Diplomas and transcripts must also be submitted in the original language, if not in English or Scandinavian. We only accept applications and documentation sent via Jobbnorge within the application deadline.

About the Department/Section/Group

The Faculty of Health Sciences at UiT The Arctic University of Norway represents a newly created entity gathering almost all possible health study programs. This facilitates an unique interdisciplinarity and innovation in health education and research. We work closely with the services in the North to solve tomorrow's challenges.

About the Employer:

Note or Other details

We offer

  • Involvement in an interesting research project
  • Good career opportunities
  • A good academic environment with dedicated colleagues
  • Flexible working hours and a state collective pay agreement
  • Pension scheme through the state pension fund
  • More practical information for working and living in Norway can be found here: https://uit.no/staffmobility

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Contact details

For further information about the positions and project, please contact post doctor Omri Snir:

or the group´s current leader professor John-Bjarne Hansen

General questions are to be directed to the Head of Office Arvid Inge Paulsen e-mail: [email protected].

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